Aloe and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Aloe (aloe), especially for people who are male, 60+ old, also take Acetaminophen, and have Nausea and vomiting.

The study is created by eHealthMe based on reports of 2,068 people who have side effects when taking Aloe from the FDA, and is updated regularly.

What is Aloe?

Aloe has active ingredients of aloe. eHealthMe is studying from 2,128 Aloe users. Check the latest studies of Aloe.

On Aug, 05, 2026

2,068 people reported to have side effects when taking Aloe.
Among them, 78 people (3.77%) died.

Among these 78 people:

What is the gender of people who died when taking Aloe? *

female: 13.51 %
male: 86.49 %

What is the age of people who died when taking Aloe? *

What are other drugs people take besides Aloe? *

Acetaminophen: 53 people, 67.95%
Gabapentin: 50 people, 64.10%
Melatonin: 50 people, 64.10%
Ondansetron: 50 people, 64.10%
Allopurinol: 49 people, 62.82%
Simvastatin: 48 people, 61.54%
Atrovent: 48 people, 61.54%
Metronidazole: 48 people, 61.54%
Phytonadione: 48 people, 61.54%
Polyethylene Glycol 3350: 48 people, 61.54%

What are other side effects people have before they died? *

Sepsis (a severe blood infection that can lead to organ failure and death): 43 people, 55.13%
Nausea And Vomiting: 42 people, 53.85%
Abdominal Distension: 41 people, 52.56%
Stress And Anxiety: 41 people, 52.56%
Cardiogenic Shock (inadequate circulation of blood): 41 people, 52.56%
Drug Hypersensitivity: 40 people, 51.28%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 39 people, 50.00%
Drowsiness: 39 people, 50.00%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 39 people, 50.00%
Ventricular Fibrillation (abnormally irregular heart rhythm): 39 people, 50.00%

What are the existing conditions these people have? *

Nausea And Vomiting: 50 people, 64.10%
Ventricular Fibrillation (abnormally irregular heart rhythm): 48 people, 61.54%
Bacterial Infection: 48 people, 61.54%
Thrombosis (formation of a blood clot inside a blood vessel): 48 people, 61.54%
Swelling: 48 people, 61.54%
Sleep Disorder: 48 people, 61.54%
Blood Phosphorus Increased: 48 people, 61.54%
Blood Uric Acid Increased: 48 people, 61.54%
Neuralgia (pain in one or more nerves): 48 people, 61.54%
Iron Deficiency: 48 people, 61.54%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aloe:

Aloe (2,128 reports)

Expand to all the drugs that have ingredients of aloe:

Death and drugs with ingredients of aloe (78 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aloe:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,115 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aloe (the active ingredients of Aloe) and Aloe (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.