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Aloe and Insomnia - a phase IV clinical study of FDA data

Summary:

Insomnia is reported as a side effect among people who take Aloe (aloe), especially for people who are female, 60+ old, also take Vitamin D3, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Insomnia when taking Aloe. It is created by eHealthMe based on reports of 2,068 people who have side effects when taking Aloe from the FDA, and is updated regularly.

What is Aloe?

Aloe has active ingredients of aloe. eHealthMe is studying from 2,128 Aloe users. Check the latest studies of Aloe.

What is Insomnia?

Insomnia (sleeplessness) is found to be associated with 3,118 drugs and 5,169 conditions by eHealthMe. Check the latest studies of Insomnia.

On Jul, 13, 2026

2,068 people reported to have side effects when taking Aloe.
Among them, 71 people (3.43%) have Insomnia.

Could Aloe cause Insomnia?

Among these 71 people:

What is the gender of people who have Insomnia when taking Aloe? *

  • female: 80.28 %
  • male: 19.72 %

What is the age of people who have Insomnia when taking Aloe? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.64 %
  • 20-29: 7.27 %
  • 30-39: 7.27 %
  • 40-49: 9.09 %
  • 50-59: 20.0 %
  • 60+: 52.73 %

What are other drugs people take besides Aloe? *

  1. Vitamin D3: 14 people, 19.72%
  2. Revlimid: 13 people, 18.31%
  3. Vitamin C: 12 people, 16.90%
  4. Magnesium: 10 people, 14.08%
  5. Probiotic: 10 people, 14.08%
  6. Flonase Allergy Relief: 9 people, 12.68%
  7. Zyrtec: 8 people, 11.27%
  8. Amlodipine: 8 people, 11.27%
  9. Dexamethasone: 8 people, 11.27%
  10. Velcade: 7 people, 9.86%

What are other side effects people have besides Insomnia? *

  1. Headache (pain in head): 32 people, 45.07%
  2. Nausea (feeling of having an urge to vomit): 29 people, 40.85%
  3. Fatigue (feeling of tiredness): 26 people, 36.62%
  4. Diarrhea: 25 people, 35.21%
  5. Itching: 19 people, 26.76%
  6. Dry Skin: 15 people, 21.13%
  7. Constipation: 15 people, 21.13%
  8. Dizziness: 15 people, 21.13%
  9. Back Pain: 14 people, 19.72%
  10. Pain: 14 people, 19.72%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 13 people, 18.31%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 9.86%
  3. Ovarian Cancer (cancer of ovary): 6 people, 8.45%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 7.04%
  5. Drowsiness: 5 people, 7.04%
  6. Stress And Anxiety: 5 people, 7.04%
  7. Upper Respiratory Tract Infection: 5 people, 7.04%
  8. Seasonal Allergy (allergic condition due to certain season): 5 people, 7.04%
  9. Parkinson's Disease: 5 people, 7.04%
  10. Thyroid Cancer: 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

Do you take Aloe and have Insomnia?

- Check whether Insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aloe:

  • Aloe (2,128 reports)

Insomnia treatments and more:

How severe was Insomnia and when was it recovered:

Expand to all the drugs that have ingredients of aloe:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aloe:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia:

Browse all the conditions that are associated with Insomnia:

How the study uses the data?

The study uses data from the FDA. It is based on aloe (the active ingredients of Aloe) and Aloe (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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