Aloxi and Appendicitis perforated - a phase IV clinical study of FDA data

Summary:

Appendicitis perforated is reported as a side effect among people who take Aloxi (palonosetron hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Doxil, and have Bone disorder.

The phase IV clinical study analyzes which people have Appendicitis perforated when taking Aloxi. It is created by eHealthMe based on reports of 8,990 people who have side effects when taking Aloxi from the FDA, and is updated regularly.

What is Aloxi?

Aloxi has active ingredients of palonosetron hydrochloride. eHealthMe is studying from 9,072 Aloxi users. Check the latest studies of Aloxi.

What is Appendicitis perforated?

Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts) is found to be associated with 371 drugs and 554 conditions by eHealthMe. Check the latest studies of Appendicitis perforated.

On Jul, 13, 2026

8,990 people reported to have side effects when taking Aloxi.
Among them, 14 people (0.16%) have Appendicitis perforated.

Could Aloxi cause Appendicitis perforated?

Among these 14 people:

How long have people been on Aloxi when they have Appendicitis perforated? *

What is the gender of people who have Appendicitis perforated when taking Aloxi? *

female: 92.86 %
male: 7.14 %

What is the age of people who have Appendicitis perforated when taking Aloxi? *

What are other drugs people take besides Aloxi? *

What are other side effects people have besides Appendicitis perforated? *

Sepsis (a severe blood infection that can lead to organ failure and death): 14 people, 100.00%
Appendicitis (inflammation of the appendix): 14 people, 100.00%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 13 people, 92.86%
Kidney Stones: 13 people, 92.86%
Osteomyelitis (infection of bone): 13 people, 92.86%
Nodal Osteoarthritis (a more painful form of osteoarthritis a affecting the end joints of fingers is called nodal osteoarthritis): 13 people, 92.86%
Nausea (feeling of having an urge to vomit): 13 people, 92.86%
Dermal Cyst: 13 people, 92.86%
Back Pain: 13 people, 92.86%
Metastases To Spine (cancer spreads to spine): 13 people, 92.86%

What are the existing conditions these people have? *

Bone Disorder: 4 people, 28.57%
Lung Adenocarcinoma Metastatic (a form of non-small cell lung cancer spreads to other part): 1 person, 7.14%
Cervix Carcinoma (cancer of cervix): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Aloxi and have Appendicitis perforated?

- Check whether Appendicitis perforated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aloxi:

Aloxi (9,072 reports)

Browse all side effects of Aloxi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Appendicitis perforated:

Appendicitis perforated (371 drugs)

Browse all the conditions that are associated with Appendicitis perforated:

Appendicitis perforated (554 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on palonosetron hydrochloride (the active ingredients of Aloxi) and Aloxi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.