Aloxi and Injection site induration - a phase IV clinical study of FDA data

Summary:

Injection site induration is reported as a side effect among people who take Aloxi (palonosetron hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Fosaprepitant Dimeglumine, and have Breast cancer.

The phase IV clinical study analyzes which people have Injection site induration when taking Aloxi. It is created by eHealthMe based on reports of 8,990 people who have side effects when taking Aloxi from the FDA, and is updated regularly.

What is Aloxi?

Aloxi has active ingredients of palonosetron hydrochloride. eHealthMe is studying from 9,072 Aloxi users. Check the latest studies of Aloxi.

What is Injection site induration?

Injection site induration is found to be associated with 554 drugs and 627 conditions by eHealthMe. Check the latest studies of Injection site induration.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

8,990 people reported to have side effects when taking Aloxi.
Among them, 15 people (0.17%) have Injection site induration.

Could Aloxi cause Injection site induration?

Among these 15 people:

How long have people been on Aloxi when they have Injection site induration? *

What is the gender of people who have Injection site induration when taking Aloxi? *

female: 93.33 %
male: 6.67 %

What is the age of people who have Injection site induration when taking Aloxi? *

What are other drugs people take besides Aloxi? *

Fosaprepitant Dimeglumine: 13 people, 86.67%
Epirubicin Hydrochloride: 6 people, 40.00%
Decadron: 5 people, 33.33%
Cyclophosphamide: 5 people, 33.33%
Fluorouracil: 2 people, 13.33%
Sodium Chloride: 1 person, 6.67%
Navelbine: 1 person, 6.67%
Magnesium Sulfate: 1 person, 6.67%
Emend: 1 person, 6.67%
Doxorubicin Hydrochloride: 1 person, 6.67%

What are other side effects people have besides Injection site induration? *

Injection Site Pain: 13 people, 86.67%
Injection Site Erythema (redness at injection site): 9 people, 60.00%
Injection Site Phlebitis (inflammation of the walls of a vein at injection site): 8 people, 53.33%
Malaise (a feeling of general discomfort or uneasiness): 2 people, 13.33%
Injection Site Vasculitis (inflammation of a blood vessel at injection site): 2 people, 13.33%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 13.33%
White Blood Cell Count Decreased: 1 person, 6.67%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 1 person, 6.67%
Injection Site Vesicles (fluid- or air-filled cavity or sac at injection site): 1 person, 6.67%
Injection Site Swelling: 1 person, 6.67%

What are the existing conditions these people have? *

Breast Cancer: 10 people, 66.67%
Lung Cancer - Non-Small Cell (lung cancer): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Aloxi and have Injection site induration?

- Check whether Injection site induration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aloxi:

Aloxi (9,072 reports)

Browse all side effects of Aloxi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site induration:

Injection site induration (554 drugs)

Browse all the conditions that are associated with Injection site induration:

Injection site induration (627 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on palonosetron hydrochloride (the active ingredients of Aloxi) and Aloxi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.