Alphagan and Conjunctival haemorrhage - a phase IV clinical study of FDA data

Summary:

Conjunctival haemorrhage is reported as a side effect among people who take Alphagan (brimonidine tartrate), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Lumigan, and have Macular oedema.

The phase IV clinical study analyzes which people have Conjunctival haemorrhage when taking Alphagan. It is created by eHealthMe based on reports of 9,802 people who have side effects when taking Alphagan from the FDA, and is updated regularly.

What is Alphagan?

Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.

What is Conjunctival haemorrhage?

Conjunctival haemorrhage (bleeding underneath the conjunctiva) is found to be associated with 509 drugs and 561 conditions by eHealthMe. Check the latest studies of Conjunctival haemorrhage.

On Aug, 12, 2026

9,802 people reported to have side effects when taking Alphagan.
Among them, 16 people (0.16%) have Conjunctival haemorrhage.

Could Alphagan cause Conjunctival haemorrhage?

Among these 16 people:

How long have people been on Alphagan when they have Conjunctival haemorrhage? *

What is the gender of people who have Conjunctival haemorrhage when taking Alphagan? *

female: 30.77 %
male: 69.23 %

What is the age of people who have Conjunctival haemorrhage when taking Alphagan? *

What are other drugs people take besides Alphagan? *

What are other side effects people have besides Conjunctival haemorrhage? *

Ocular Hyperaemia (an abnormally large amount of blood in eye): 8 people, 50.00%
Fever: 6 people, 37.50%
Eye Pain: 5 people, 31.25%
Cough: 5 people, 31.25%
Intraocular Pressure Increased: 4 people, 25.00%
Blepharitis (chronic inflammation of the eyelid): 4 people, 25.00%
Hypersensitivity: 4 people, 25.00%
Eye Pruritus (eye itching): 4 people, 25.00%
Eye Haemorrhage (bleeding in the eye): 4 people, 25.00%
Erythema Of Eyelid (redness of the eyelid): 3 people, 18.75%

What are the existing conditions these people have? *

Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 3 people, 18.75%
Uveitis (inflammation of the uvea): 2 people, 12.50%
Retinal Vessel Occlusion (a blockage in one of the small arteries): 2 people, 12.50%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 12.50%
High Blood Pressure: 1 person, 6.25%
Depression: 1 person, 6.25%
Bipolar Disorder (mood disorder): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Alphagan and have Conjunctival haemorrhage?

- Check whether Conjunctival haemorrhage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alphagan:

Alphagan (9,981 reports)

Browse all side effects of Alphagan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Conjunctival haemorrhage:

Conjunctival haemorrhage (509 drugs)

Browse all the conditions that are associated with Conjunctival haemorrhage:

Conjunctival haemorrhage (561 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on brimonidine tartrate (the active ingredients of Alphagan) and Alphagan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.