Alphagan and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Alphagan (brimonidine tartrate), especially for people who are female, 60+ old, also take Xalatan, and have Metastases to bone.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Alphagan. It is created by eHealthMe based on reports of 9,802 people who have side effects when taking Alphagan from the FDA, and is updated regularly.

What is Alphagan?

Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 1,033 drugs and 1,426 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.

On Nov, 12, 2025

9,802 people reported to have side effects when taking Alphagan.
Among them, 21 people (0.21%) have Hyperthyroidism.

Among these 21 people:

What is the gender of people who have Hyperthyroidism when taking Alphagan? *

female: 76.19 %
male: 23.81 %

What is the age of people who have Hyperthyroidism when taking Alphagan? *

What are other drugs people take besides Alphagan? *

What are other side effects people have besides Hyperthyroidism? *

Enlarged Heart: 8 people, 38.10%
Weakness: 8 people, 38.10%
Dizziness: 7 people, 33.33%
Osteoporosis (bones weak and more likely to break): 7 people, 33.33%
Urinary Tract Infection: 7 people, 33.33%
Fall: 7 people, 33.33%
Oedema Peripheral (superficial swelling): 7 people, 33.33%
Depression: 7 people, 33.33%
Fistula (an abnormal connection or passageway between two): 6 people, 28.57%
Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 6 people, 28.57%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 6 people, 28.57%
Osteoporosis (bones weak and more likely to break): 5 people, 23.81%
Uveitis (inflammation of the uvea): 3 people, 14.29%
Type 2 Diabetes: 2 people, 9.52%
Supraventricular Tachyarrhythmia (rapid heart rhythm originating at or above the atrioventricular node): 2 people, 9.52%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 9.52%
High Blood Cholesterol: 2 people, 9.52%
High Blood Pressure: 1 person, 4.76%
Diabetes: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Alphagan and have Hyperthyroidism?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alphagan:

Alphagan (9,981 reports)

Hyperthyroidism treatments and more:

Hyperthyroidism (26,829 reports)

Browse all side effects of Alphagan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Hyperthyroidism (1,033 drugs)

Browse all the conditions that are associated with Hyperthyroidism:

Hyperthyroidism (1,426 conditions)

Drugs similar to Alphagan and Hyperthyroidism :

Related publications that referenced our studies

Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .
Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on brimonidine tartrate (the active ingredients of Alphagan) and Alphagan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.