Alphagan and Sciatica aggravated - a phase IV clinical study of FDA data

Summary:

Sciatica aggravated is reported as a side effect among people who take Alphagan (brimonidine tartrate), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Neurontin, and have Pain.

The phase IV clinical study analyzes which people have Sciatica aggravated when taking Alphagan. It is created by eHealthMe based on reports of 9,802 people who have side effects when taking Alphagan from the FDA, and is updated regularly.

What is Alphagan?

Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.

What is Sciatica aggravated?

Sciatica aggravated (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,059 drugs and 397 conditions by eHealthMe. Check the latest studies of Sciatica aggravated.

On Jan, 21, 2026

9,802 people reported to have side effects when taking Alphagan.
Among them, 25 people (0.26%) have Sciatica aggravated.

Could Alphagan cause Sciatica aggravated?

Among these 25 people:

How long have people been on Alphagan when they have Sciatica aggravated? *

What is the gender of people who have Sciatica aggravated when taking Alphagan? *

female: 48 %
male: 52 %

What is the age of people who have Sciatica aggravated when taking Alphagan? *

What are other drugs people take besides Alphagan? *

What are other side effects people have besides Sciatica aggravated? *

Joint Pain: 13 people, 52.00%
Pain: 13 people, 52.00%
Urinary Tract Infection: 13 people, 52.00%
Cough: 12 people, 48.00%
Fall: 12 people, 48.00%
High Blood Pressure: 12 people, 48.00%
Stress And Anxiety: 12 people, 48.00%
Oedema Peripheral (superficial swelling): 11 people, 44.00%
Indigestion: 11 people, 44.00%
Pain In Extremity: 11 people, 44.00%

What are the existing conditions these people have? *

Pain: 12 people, 48.00%
High Blood Pressure: 3 people, 12.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 12.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 12.00%
Hypersensitivity: 2 people, 8.00%
Depression: 2 people, 8.00%
Eye Disorder: 2 people, 8.00%
Enlarged Prostate: 1 person, 4.00%
High Blood Cholesterol: 1 person, 4.00%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Alphagan and have Sciatica aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alphagan:

Alphagan (9,981 reports)

Browse all side effects of Alphagan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica aggravated:

Sciatica aggravated (1,060 drugs)

Browse all the conditions that are associated with Sciatica aggravated:

Sciatica aggravated (397 conditions)

Drugs similar to Alphagan and Sciatica aggravated :

How the study uses the data?

The study uses data from the FDA. It is based on brimonidine tartrate (the active ingredients of Alphagan) and Alphagan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.