Alphagan and Thyroid function test abnormal - a phase IV clinical study of FDA data

Summary:

Thyroid function test abnormal is reported as a side effect among people who take Alphagan (brimonidine tartrate), especially for people who are female, 60+ old, also take Cosopt, and have Metastases to liver.

The phase IV clinical study analyzes which people have Thyroid function test abnormal when taking Alphagan. It is created by eHealthMe based on reports of 9,802 people who have side effects when taking Alphagan from the FDA, and is updated regularly.

What is Alphagan?

Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.

What is Thyroid function test abnormal?

Thyroid function test abnormal is found to be associated with 1,717 drugs and 1,580 conditions by eHealthMe. Check the latest studies of Thyroid function test abnormal.

On Oct, 15, 2025

9,802 people reported to have side effects when taking Alphagan.
Among them, 12 people (0.12%) have Thyroid function test abnormal.

Could Alphagan cause Thyroid function test abnormal?

Among these 12 people:

What is the gender of people who have Thyroid function test abnormal when taking Alphagan? *

female: 63.64 %
male: 36.36 %

What is the age of people who have Thyroid function test abnormal when taking Alphagan? *

What are other drugs people take besides Alphagan? *

What are other side effects people have besides Thyroid function test abnormal? *

Pain In Extremity: 4 people, 33.33%
Pain: 4 people, 33.33%
Vision Blurred: 4 people, 33.33%
Fatigue (feeling of tiredness): 4 people, 33.33%
Intraocular Pressure Increased: 4 people, 33.33%
Wound: 3 people, 25.00%
Electrolyte Depletion (act of decreasing electrolyte markedly): 3 people, 25.00%
Oedema Peripheral (superficial swelling): 3 people, 25.00%
Nausea (feeling of having an urge to vomit): 3 people, 25.00%
Diarrhea: 3 people, 25.00%

What are the existing conditions these people have? *

Renal Cell Carcinoma (a kidney cancer): 3 people, 25.00%
Metastases To Pancreas (cancer spreads to pancreas): 3 people, 25.00%
Metastases To Liver (cancer spreads to liver): 3 people, 25.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 16.67%
High Blood Pressure: 2 people, 16.67%
Diabetes: 2 people, 16.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 8.33%
Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 8.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
Heart Rate Increased: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Alphagan and have Thyroid function test abnormal?

- Check whether Thyroid function test abnormal is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alphagan:

Alphagan (9,981 reports)

Browse all side effects of Alphagan:

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Browse all the drugs that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,717 drugs)

Browse all the conditions that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,580 conditions)

Drugs similar to Alphagan and Thyroid function test abnormal :

How the study uses the data?

The study uses data from the FDA. It is based on brimonidine tartrate (the active ingredients of Alphagan) and Alphagan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.