Alprazolam and Localised oedema - a phase IV clinical study of FDA data

Summary:

Localised oedema is reported as a side effect among people who take Alprazolam (alprazolam), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Revatio, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Localised oedema when taking Alprazolam. It is created by eHealthMe based on reports of 132,238 people who have side effects when taking Alprazolam from the FDA, and is updated regularly.

What is Alprazolam?

Alprazolam has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 134,864 Alprazolam users. Check the latest studies of Alprazolam.

What is Localised oedema?

Localised oedema (fluid retention in a particular part of the body) is found to be associated with 544 drugs and 707 conditions by eHealthMe. Check the latest studies of Localised oedema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

132,238 people reported to have side effects when taking Alprazolam.
Among them, 44 people (0.03%) have Localised oedema.

Could Alprazolam cause Localised oedema?

Among these 44 people:

How long have people been on Alprazolam when they have Localised oedema? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Localised oedema when taking Alprazolam? *

  • female: 75 %
  • male: 25 %

What is the age of people who have Localised oedema when taking Alprazolam? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 27.5 %
  • 30-39: 7.5 %
  • 40-49: 27.5 %
  • 50-59: 17.5 %
  • 60+: 20.0 %

What are other drugs people take besides Alprazolam? *

  1. Revatio: 12 people, 27.27%
  2. Biotin: 11 people, 25.00%
  3. Celebrex: 9 people, 20.45%
  4. Aciphex: 9 people, 20.45%
  5. Xarelto: 9 people, 20.45%
  6. Orenitram: 9 people, 20.45%
  7. Invanz: 9 people, 20.45%
  8. Promethazine: 9 people, 20.45%
  9. Requip: 9 people, 20.45%
  10. Ativan: 9 people, 20.45%

What are other side effects people have besides Localised oedema? *

  1. Rashes (redness): 28 people, 63.64%
  2. Skin Exfoliation (removal of the oldest dead skin cells): 17 people, 38.64%
  3. Dyspnea (difficult or laboured breathing): 17 people, 38.64%
  4. Itching: 16 people, 36.36%
  5. Fainting (loss of consciousness and postural tone): 14 people, 31.82%
  6. Dizziness: 13 people, 29.55%
  7. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 12 people, 27.27%
  8. Blepharitis (chronic inflammation of the eyelid): 12 people, 27.27%
  9. Oedema Peripheral (superficial swelling): 12 people, 27.27%
  10. Pain: 12 people, 27.27%

What are the existing conditions these people have? *

  1. Pulmonary Hypertension (increase in blood pressure in the lung artery): 9 people, 20.45%
  2. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 20.45%
  3. High Blood Pressure: 5 people, 11.36%
  4. Oedema (fluid collection in tissue): 4 people, 9.09%
  5. Pain: 3 people, 6.82%
  6. Hypersensitivity: 3 people, 6.82%
  7. Cough: 3 people, 6.82%
  8. Wheezing (a high-pitched whistling sound made while you breath): 3 people, 6.82%
  9. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 4.55%
  10. Depression: 2 people, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Alprazolam and have Localised oedema?

- Check whether Localised oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Alprazolam:

Localised oedema treatments and more:

How severe was Localised oedema and when was it recovered:

Expand to all the drugs that have ingredients of alprazolam:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alprazolam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Localised oedema:

Browse all the conditions that are associated with Localised oedema:


How the study uses the data?

The study uses data from the FDA. It is based on alprazolam (the active ingredients of Alprazolam) and Alprazolam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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