Altace and Intervertebral disc space narrowing - a phase IV clinical study of FDA data

Summary:

Intervertebral disc space narrowing is reported as a side effect among people who take Altace (ramipril), especially for people who are male, 60+ old, also take Zometa, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Intervertebral disc space narrowing when taking Altace. It is created by eHealthMe based on reports of 23,086 people who have side effects when taking Altace from the FDA, and is updated regularly.

What is Altace?

Altace has active ingredients of ramipril. It is often used in high blood pressure. eHealthMe is studying from 23,681 Altace users. Check the latest studies of Altace.

What is Intervertebral disc space narrowing?

Intervertebral disc space narrowing (spinal disc space narrowing) is found to be associated with 452 drugs and 316 conditions by eHealthMe. Check the latest studies of Intervertebral disc space narrowing.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

23,086 people reported to have side effects when taking Altace.
Among them, 19 people (0.08%) have Intervertebral disc space narrowing.

Could Altace cause Intervertebral disc space narrowing?

Among these 19 people:

What is the gender of people who have Intervertebral disc space narrowing when taking Altace? *

  • female: 21.05 %
  • male: 78.95 %

What is the age of people who have Intervertebral disc space narrowing when taking Altace? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 5.88 %
  • 40-49: 0.0 %
  • 50-59: 11.76 %
  • 60+: 82.35 %

What are other drugs people take besides Altace? *

  1. Zometa: 17 people, 89.47%
  2. Prilosec: 16 people, 84.21%
  3. Lipitor: 15 people, 78.95%
  4. Aredia: 14 people, 73.68%
  5. Spironolactone: 14 people, 73.68%
  6. Metronidazole: 13 people, 68.42%
  7. Warfarin Sodium: 13 people, 68.42%
  8. Amoxicillin: 13 people, 68.42%
  9. Coreg: 13 people, 68.42%
  10. Azithromycin: 13 people, 68.42%

What are other side effects people have besides Intervertebral disc space narrowing? *

  1. Joint Pain: 18 people, 94.74%
  2. Intervertebral Disc Degeneration (spinal disc degeneration): 18 people, 94.74%
  3. Head Injury: 17 people, 89.47%
  4. Hyperlipidaemia (presence of excess lipids in the blood): 16 people, 84.21%
  5. Neck Pain: 16 people, 84.21%
  6. Exostosis (formation of new bone on the surface of a bone): 16 people, 84.21%
  7. Stress And Anxiety: 16 people, 84.21%
  8. Muscle Spasms (muscle contraction): 16 people, 84.21%
  9. Spinal Osteoarthritis (joint cartilage loss in spine): 16 people, 84.21%
  10. Bone Disorder: 15 people, 78.95%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 15 people, 78.95%
  2. High Blood Cholesterol: 13 people, 68.42%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 13 people, 68.42%
  4. Pain: 4 people, 21.05%
  5. Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups): 3 people, 15.79%
  6. Cardiac Disorder: 1 person, 5.26%
  7. Constipation: 1 person, 5.26%
  8. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 5.26%
  9. Faeces Hard: 1 person, 5.26%
  10. Heart Rate Irregular: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Altace and have Intervertebral disc space narrowing?

- Check whether Intervertebral disc space narrowing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Altace:

Intervertebral disc space narrowing treatments and more:

How severe was Intervertebral disc space narrowing and when was it recovered:

Expand to all the drugs that have ingredients of ramipril:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Altace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intervertebral disc space narrowing:

Browse all the conditions that are associated with Intervertebral disc space narrowing:


How the study uses the data?

The study uses data from the FDA. It is based on ramipril (the active ingredients of Altace) and Altace (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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