Amaryl and Acne - a phase IV clinical study of FDA data

Summary:

Acne is reported as a side effect among people who take Amaryl (glimepiride), especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years also take Metformin, and have Pain.

The phase IV clinical study analyzes which people have Acne when taking Amaryl. It is created by eHealthMe based on reports of 31,980 people who have side effects when taking Amaryl from the FDA, and is updated regularly.

What is Amaryl?

Amaryl has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 32,259 Amaryl users. Check the latest studies of Amaryl.

What is Acne?

Acne (skin problems that cause pimples) is found to be associated with 1,313 drugs and 2,347 conditions by eHealthMe. Check the latest studies of Acne.



On Jul, 17, 2026

31,980 people reported to have side effects when taking Amaryl.
Among them, 12 people (0.04%) have Acne.

Could Amaryl cause Acne?

Among these 12 people:

How long have people been on Amaryl when they have Acne? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Acne when taking Amaryl? *

  • female: 54.55 %
  • male: 45.45 %

What is the age of people who have Acne when taking Amaryl? *

  • 0-1: 0.0 %
  • 2-9: 9.09 %
  • 10-19: 0.0 %
  • 20-29: 9.09 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 45.45 %
  • 60+: 36.36 %

What are other drugs people take besides Amaryl? *

  1. Metformin: 5 people, 41.67%
  2. Vitamin D3: 3 people, 25.00%
  3. Lescol: 2 people, 16.67%
  4. Amlodipine: 2 people, 16.67%
  5. Xeloda: 2 people, 16.67%
  6. Avastin: 2 people, 16.67%
  7. Lantus: 2 people, 16.67%
  8. Cozaar: 2 people, 16.67%
  9. Glucophage: 1 person, 8.33%
  10. Humira: 1 person, 8.33%

What are other side effects people have besides Acne? *

  1. Nausea (feeling of having an urge to vomit): 3 people, 25.00%
  2. Stomatitis (inflammation of mucous membrane of mouth): 3 people, 25.00%
  3. Hair Loss: 3 people, 25.00%
  4. Pain: 3 people, 25.00%
  5. Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 16.67%
  6. Skin Toxicity (skin damage due to toxin/poison): 2 people, 16.67%
  7. Dry Skin: 2 people, 16.67%
  8. Osteomyelitis (infection of bone): 2 people, 16.67%
  9. Constipation: 2 people, 16.67%
  10. Fatigue (feeling of tiredness): 2 people, 16.67%

What are the existing conditions these people have? *

  1. Pain: 2 people, 16.67%
  2. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 8.33%
  3. Renal Cancer Stage Iv (the tumour has spread to areas beyond gerota's fascia and extends into the adrenal gland on the same side of the body as the tumour, possibly to lymph nodes, but not to other parts of the body): 1 person, 8.33%
  4. Pancreatic Neuroendocrine Tumor: 1 person, 8.33%
  5. Osteoporosis (bones weak and more likely to break): 1 person, 8.33%
  6. Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 8.33%
  7. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 1 person, 8.33%
  8. Nausea (feeling of having an urge to vomit): 1 person, 8.33%
  9. Muscle Spasms (muscle contraction): 1 person, 8.33%
  10. Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Amaryl and have Acne?

- Check whether Acne is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amaryl:

Acne treatments and more:

  • Acne (179,011 reports)

How severe was Acne and when was it recovered:

Expand to all the drugs that have ingredients of glimepiride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amaryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acne:

  • Acne (1,313 drugs)

Browse all the conditions that are associated with Acne:

  • Acne (2,347 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on glimepiride (the active ingredients of Amaryl) and Amaryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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