Amaryl and Acute hepatic failure - a phase IV clinical study of FDA data

Summary:

Acute hepatic failure is reported as a side effect among people who take Amaryl (glimepiride), especially for people who are male, 50-59 old, also take Actos, and have Ascites.

The phase IV clinical study analyzes which people have Acute hepatic failure when taking Amaryl. It is created by eHealthMe based on reports of 31,980 people who have side effects when taking Amaryl from the FDA, and is updated regularly.

What is Amaryl?

Amaryl has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 32,259 Amaryl users. Check the latest studies of Amaryl.

What is Acute hepatic failure?

Acute hepatic failure is found to be associated with 710 drugs and 1,182 conditions by eHealthMe. Check the latest studies of Acute hepatic failure.

On Jul, 27, 2026

31,980 people reported to have side effects when taking Amaryl.
Among them, 20 people (0.06%) have Acute hepatic failure.

Could Amaryl cause Acute hepatic failure?

Among these 20 people:

What is the gender of people who have Acute hepatic failure when taking Amaryl? *

female: 17.65 %
male: 82.35 %

What is the age of people who have Acute hepatic failure when taking Amaryl? *

What are other drugs people take besides Amaryl? *

What are other side effects people have besides Acute hepatic failure? *

Hypoglycemia (low blood sugar): 9 people, 45.00%
Gastric Haemorrhage (bleeding stomach): 7 people, 35.00%
Bleeding Disorders: 6 people, 30.00%
Multi-Organ Failure (multisystem organ failure): 4 people, 20.00%
Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 4 people, 20.00%
Nausea And Vomiting: 4 people, 20.00%
Acute Kidney Failure: 3 people, 15.00%
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 3 people, 15.00%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 3 people, 15.00%
Lactic Acidosis (low ph in body tissues): 3 people, 15.00%

What are the existing conditions these people have? *

Hepatitis B: 9 people, 45.00%
Hepatic Neoplasm Malignant (liver cancer): 9 people, 45.00%
Ascites (accumulation of fluid in the abdominal cavity): 9 people, 45.00%
High Blood Pressure: 8 people, 40.00%
Stable Angina (a constant chest pain): 2 people, 10.00%
Rectal Cancer Metastatic (cancer of rectum spreads to other): 2 people, 10.00%
Enlarged Prostate: 2 people, 10.00%
Dyslipidaemia (abnormal amount of lipids): 2 people, 10.00%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 5.00%
Malaria (a parasitic disease due to mosquito bite): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Amaryl and have Acute hepatic failure?

- Check whether Acute hepatic failure is associated with a drug or a condition
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- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amaryl:

Amaryl (32,259 reports)

Browse all side effects of Amaryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute hepatic failure:

Acute hepatic failure (710 drugs)

Browse all the conditions that are associated with Acute hepatic failure:

Acute hepatic failure (1,182 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on glimepiride (the active ingredients of Amaryl) and Amaryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.