Amaryl and Hiatal hernia - a phase IV clinical study of FDA data

Summary:

Hiatal hernia is reported as a side effect among people who take Amaryl (glimepiride), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Plavix, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Hiatal hernia when taking Amaryl. It is created by eHealthMe based on reports of 31,980 people who have side effects when taking Amaryl from the FDA, and is updated regularly.

What is Amaryl?

Amaryl has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 32,259 Amaryl users. Check the latest studies of Amaryl.

What is Hiatal hernia?

Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm) is found to be associated with 1,304 drugs and 1,564 conditions by eHealthMe. Check the latest studies of Hiatal hernia.

On Jul, 11, 2026

31,980 people reported to have side effects when taking Amaryl.
Among them, 85 people (0.27%) have Hiatal hernia.

Among these 85 people:

How long have people been on Amaryl when they have Hiatal hernia? *

What is the gender of people who have Hiatal hernia when taking Amaryl? *

female: 67.9 %
male: 32.1 %

What is the age of people who have Hiatal hernia when taking Amaryl? *

What are other drugs people take besides Amaryl? *

What are other side effects people have besides Hiatal hernia? *

Chest Pain: 34 people, 40.00%
Dyspnea (difficult or laboured breathing): 33 people, 38.82%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 31 people, 36.47%
Nausea (feeling of having an urge to vomit): 29 people, 34.12%
Stress And Anxiety: 25 people, 29.41%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 24 people, 28.24%
Anaemia (lack of blood): 23 people, 27.06%
Pain: 23 people, 27.06%
Urinary Tract Infection: 23 people, 27.06%
Joint Pain: 22 people, 25.88%

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 11.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 11.76%
Breast Cancer Metastatic: 9 people, 10.59%
Local Anaesthesia: 7 people, 8.24%
Metastases To Bone (cancer spreads to bone): 7 people, 8.24%
Back Pain: 7 people, 8.24%
Pain: 6 people, 7.06%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 7.06%
Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 5.88%
Osteoporosis (bones weak and more likely to break): 5 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Amaryl and have Hiatal hernia?

- Check whether Hiatal hernia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amaryl:

Amaryl (32,259 reports)

Hiatal hernia treatments and more:

Hiatal hernia (28,705 reports)

Browse all side effects of Amaryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hiatal hernia:

Hiatal hernia (1,304 drugs)

Browse all the conditions that are associated with Hiatal hernia:

Hiatal hernia (1,564 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on glimepiride (the active ingredients of Amaryl) and Amaryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.