Ambien and Bladder discomfort - a phase IV clinical study of FDA data

Summary:

Bladder discomfort is reported as a side effect among people who take Ambien (zolpidem tartrate), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Alprazolam, and have Blood pressure abnormal.

The phase IV clinical study analyzes which people have Bladder discomfort when taking Ambien. It is created by eHealthMe based on reports of 86,763 people who have side effects when taking Ambien from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

What is Bladder discomfort?

Bladder discomfort is found to be associated with 206 drugs and 304 conditions by eHealthMe. Check the latest studies of Bladder discomfort.

On Jul, 28, 2026

86,763 people reported to have side effects when taking Ambien.
Among them, 25 people (0.03%) have Bladder discomfort.

Among these 25 people:

How long have people been on Ambien when they have Bladder discomfort? *

What is the gender of people who have Bladder discomfort when taking Ambien? *

female: 56 %
male: 44 %

What is the age of people who have Bladder discomfort when taking Ambien? *

What are other drugs people take besides Ambien? *

What are other side effects people have besides Bladder discomfort? *

Abdominal Discomfort: 16 people, 64.00%
Urination - Painful: 15 people, 60.00%
Nausea (feeling of having an urge to vomit): 15 people, 60.00%
Headache (pain in head): 14 people, 56.00%
Gait Disturbance: 14 people, 56.00%
Stress And Anxiety: 14 people, 56.00%
Malaise (a feeling of general discomfort or uneasiness): 12 people, 48.00%
Dizziness: 12 people, 48.00%
Diarrhea: 11 people, 44.00%
Back Pain: 11 people, 44.00%

What are the existing conditions these people have? *

Blood Pressure Abnormal: 10 people, 40.00%
Prostatic Disorder: 9 people, 36.00%
Dementia (madness): 9 people, 36.00%
Cardiac Disorder: 8 people, 32.00%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 8 people, 32.00%
Memory Loss: 7 people, 28.00%
Stress And Anxiety: 7 people, 28.00%
Urine Flow Decreased: 6 people, 24.00%
High Blood Pressure: 5 people, 20.00%
Gait Disturbance: 3 people, 12.00%

* Approximation only. Some reports may have incomplete information.

Do you take Ambien and have Bladder discomfort?

- Check whether Bladder discomfort is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ambien:

Ambien (93,519 reports)

Browse all side effects of Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bladder discomfort:

Bladder discomfort (206 drugs)

Browse all the conditions that are associated with Bladder discomfort:

Bladder discomfort (304 conditions)

Related publications that referenced our studies

Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Ambien) and Ambien (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.