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Ambien and Excessive eye blinking - a phase IV clinical study of FDA data

Summary:

Excessive eye blinking is reported as a side effect among people who take Ambien (zolpidem tartrate), especially for people who are male, 60+ old, also take Metoclopramide, and have Nausea.

The phase IV clinical study analyzes which people have Excessive eye blinking when taking Ambien. It is created by eHealthMe based on reports of 86,763 people who have side effects when taking Ambien from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

What is Excessive eye blinking?

Excessive eye blinking (excessive blinking is dry eyes) is found to be associated with 207 drugs and 410 conditions by eHealthMe. Check the latest studies of Excessive eye blinking.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

86,763 people reported to have side effects when taking Ambien.
Among them, 18 people (0.02%) have Excessive eye blinking.

Could Ambien cause Excessive eye blinking?

Among these 18 people:

What is the gender of people who have Excessive eye blinking when taking Ambien? *

  • female: 44.44 %
  • male: 55.56 %

What is the age of people who have Excessive eye blinking when taking Ambien? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 14.29 %
  • 40-49: 0.0 %
  • 50-59: 42.86 %
  • 60+: 42.86 %

What are other drugs people take besides Ambien? *

  1. Metoclopramide: 13 people, 72.22%
  2. Neurontin: 9 people, 50.00%
  3. Nexium: 8 people, 44.44%
  4. Diazepam: 8 people, 44.44%
  5. Carafate: 7 people, 38.89%
  6. Elavil: 7 people, 38.89%
  7. Zyprexa: 6 people, 33.33%
  8. Clonidine: 6 people, 33.33%
  9. Simvastatin: 6 people, 33.33%
  10. Imitrex: 6 people, 33.33%

What are other side effects people have besides Excessive eye blinking? *

  1. Tardive Dyskinesia (a disorder that involves involuntary movements): 14 people, 77.78%
  2. Stress And Anxiety: 12 people, 66.67%
  3. Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 12 people, 66.67%
  4. Pain: 11 people, 61.11%
  5. Depression: 10 people, 55.56%
  6. Dyskinesia (abnormality or impairment of voluntary movement): 10 people, 55.56%
  7. Headache (pain in head): 7 people, 38.89%
  8. Pain In Extremity: 7 people, 38.89%
  9. Post-Traumatic Stress Disorder: 6 people, 33.33%
  10. Joint Pain: 6 people, 33.33%

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 4 people, 22.22%
  2. Nausea And Vomiting: 2 people, 11.11%
  3. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 11.11%
  4. Mood Swings (an extreme or rapid change in mood): 1 person, 5.56%
  5. Impaired Gastric Emptying: 1 person, 5.56%
  6. Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 1 person, 5.56%
  7. Gastric Ulcer (stomach ulcer): 1 person, 5.56%
  8. Depression: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Ambien and have Excessive eye blinking?

- Check whether Excessive eye blinking is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ambien:

Excessive eye blinking treatments and more:

How severe was Excessive eye blinking and when was it recovered:

Expand to all the drugs that have ingredients of zolpidem tartrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Excessive eye blinking:

Browse all the conditions that are associated with Excessive eye blinking:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Ambien) and Ambien (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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