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Ambien and Haemoglobinuria - a phase IV clinical study of FDA data

Summary:

Haemoglobinuria is reported as a side effect among people who take Ambien (zolpidem tartrate), especially for people who are male, 50-59 old, also take Soliris, and have Paroxysmal nocturnal haemoglobinuria.

The phase IV clinical study analyzes which people have Haemoglobinuria when taking Ambien. It is created by eHealthMe based on reports of 86,763 people who have side effects when taking Ambien from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

What is Haemoglobinuria?

Haemoglobinuria (the presence of free haemoglobin in the urine) is found to be associated with 86 drugs and 249 conditions by eHealthMe. Check the latest studies of Haemoglobinuria.

On Aug, 05, 2026

86,763 people reported to have side effects when taking Ambien.
Among them, 23 people (0.03%) have Haemoglobinuria.

Could Ambien cause Haemoglobinuria?

Among these 23 people:

What is the gender of people who have Haemoglobinuria when taking Ambien? *

  • female: 33.33 %
  • male: 66.67 %

What is the age of people who have Haemoglobinuria when taking Ambien? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6.25 %
  • 20-29: 6.25 %
  • 30-39: 6.25 %
  • 40-49: 0.0 %
  • 50-59: 50.0 %
  • 60+: 31.25 %

What are other drugs people take besides Ambien? *

  1. Soliris: 21 people, 91.30%
  2. Folic Acid: 16 people, 69.57%
  3. Furosemide: 10 people, 43.48%
  4. Coreg: 10 people, 43.48%
  5. Metoprolol Tartrate: 9 people, 39.13%
  6. Norvasc: 8 people, 34.78%
  7. Benazepril Hydrochloride: 6 people, 26.09%
  8. Prilosec: 4 people, 17.39%
  9. Lipitor: 4 people, 17.39%
  10. Altace: 4 people, 17.39%

What are other side effects people have besides Haemoglobinuria? *

  1. Oedema Peripheral (superficial swelling): 10 people, 43.48%
  2. Pain: 10 people, 43.48%
  3. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 10 people, 43.48%
  4. Rashes (redness): 9 people, 39.13%
  5. Erection Problems: 9 people, 39.13%
  6. Joint Warmth: 9 people, 39.13%
  7. The Flu (the flu is caused by an influenza virus): 9 people, 39.13%
  8. Weight Decreased: 8 people, 34.78%
  9. Fatigue (feeling of tiredness): 8 people, 34.78%
  10. Post Procedural Haematoma (post procedural clotting of blood): 8 people, 34.78%

What are the existing conditions these people have? *

  1. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 22 people, 95.65%
  2. Pain: 3 people, 13.04%
  3. High Blood Pressure: 3 people, 13.04%
  4. Cardiac Disorder: 2 people, 8.70%
  5. Urinary Tract Infection: 1 person, 4.35%
  6. Nausea And Vomiting: 1 person, 4.35%
  7. Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 1 person, 4.35%
  8. Headache (pain in head): 1 person, 4.35%
  9. Dyspnea (difficult or laboured breathing): 1 person, 4.35%
  10. Depression: 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Ambien and have Haemoglobinuria?

- Check whether Haemoglobinuria is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ambien:

Haemoglobinuria treatments and more:

How severe was Haemoglobinuria and when was it recovered:

Expand to all the drugs that have ingredients of zolpidem tartrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haemoglobinuria:

Browse all the conditions that are associated with Haemoglobinuria:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Ambien) and Ambien (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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