Ambien and Insulin resistance - a phase IV clinical study of FDA data

Summary:

Insulin resistance is reported as a side effect among people who take Ambien (zolpidem tartrate), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Cymbalta, and have Hypopituitarism.

The phase IV clinical study analyzes which people have Insulin resistance when taking Ambien. It is created by eHealthMe based on reports of 86,763 people who have side effects when taking Ambien from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

What is Insulin resistance?

Insulin resistance is found to be associated with 210 drugs and 414 conditions by eHealthMe. Check the latest studies of Insulin resistance.

On Jul, 28, 2026

86,763 people reported to have side effects when taking Ambien.
Among them, 17 people (0.02%) have Insulin resistance.

Among these 17 people:

How long have people been on Ambien when they have Insulin resistance? *

What is the gender of people who have Insulin resistance when taking Ambien? *

female: 43.75 %
male: 56.25 %

What is the age of people who have Insulin resistance when taking Ambien? *

What are other drugs people take besides Ambien? *

What are other side effects people have besides Insulin resistance? *

Weight Increased: 6 people, 35.29%
Stress And Anxiety: 6 people, 35.29%
Hyperglycemia (high blood sugar): 5 people, 29.41%
High Blood Cholesterol: 5 people, 29.41%
Blood Glucose Increased: 5 people, 29.41%
Sleep Apnea Syndrome: 5 people, 29.41%
Back Pain: 5 people, 29.41%
Memory Loss: 4 people, 23.53%
Irritable Bowel Syndrome: 3 people, 17.65%
Fatigue (feeling of tiredness): 3 people, 17.65%

What are the existing conditions these people have? *

Stress And Anxiety: 3 people, 17.65%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 17.65%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 17.65%
Growth Hormone Deficiency: 3 people, 17.65%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 3 people, 17.65%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 11.76%
High Blood Pressure: 2 people, 11.76%
Depression: 2 people, 11.76%
Osteoporosis (bones weak and more likely to break): 2 people, 11.76%
Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Ambien and have Insulin resistance?

- Check whether Insulin resistance is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ambien:

Ambien (93,519 reports)

Browse all side effects of Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insulin resistance:

Insulin resistance (210 drugs)

Browse all the conditions that are associated with Insulin resistance:

Insulin resistance (414 conditions)

Related publications that referenced our studies

Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Ambien) and Ambien (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.