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Ambien and Keratitis - a phase IV clinical study of FDA data

Summary:

Keratitis is reported as a side effect among people who take Ambien (zolpidem tartrate), especially for people who are female, 50-59 old, also take Aredia, and have Metastases to bone.

The phase IV clinical study analyzes which people have Keratitis when taking Ambien. It is created by eHealthMe based on reports of 86,763 people who have side effects when taking Ambien from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,514 Ambien users. Check the latest studies of Ambien.

What is Keratitis?

Keratitis (eye's cornea, the front part of the eye, becomes inflamed) is found to be associated with 471 drugs and 827 conditions by eHealthMe. Check the latest studies of Keratitis.

On Jan, 20, 2026

86,763 people reported to have side effects when taking Ambien.
Among them, 32 people (0.04%) have Keratitis.

Could Ambien cause Keratitis?

Among these 32 people:

What is the gender of people who have Keratitis when taking Ambien? *

  • female: 96.88 %
  • male: 3.12 %

What is the age of people who have Keratitis when taking Ambien? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 24.14 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 48.28 %
  • 60+: 27.59 %

What are other drugs people take besides Ambien? *

  1. Aredia: 31 people, 96.88%
  2. Zometa: 29 people, 90.62%
  3. Prilosec: 25 people, 78.12%
  4. Xeloda: 22 people, 68.75%
  5. Celexa: 22 people, 68.75%
  6. Vioxx: 22 people, 68.75%
  7. Prozac: 22 people, 68.75%
  8. Cymbalta: 22 people, 68.75%
  9. Cytoxan: 22 people, 68.75%
  10. Reglan: 22 people, 68.75%

What are other side effects people have besides Keratitis? *

  1. Pain: 31 people, 96.88%
  2. Osteonecrosis Of Jaw (death of bone of jaw): 30 people, 93.75%
  3. Anaemia (lack of blood): 25 people, 78.12%
  4. Memory Loss: 25 people, 78.12%
  5. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 24 people, 75.00%
  6. Weakness: 23 people, 71.88%
  7. Stress And Anxiety: 23 people, 71.88%
  8. Headache (pain in head): 23 people, 71.88%
  9. Injury: 21 people, 65.62%
  10. Chest Pain: 21 people, 65.62%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 14 people, 43.75%
  2. Respiratory Tract Infection: 8 people, 25.00%
  3. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 8 people, 25.00%
  4. Psychotic Disorder: 8 people, 25.00%
  5. Pneumonia: 8 people, 25.00%
  6. Oedema (fluid collection in tissue): 8 people, 25.00%
  7. Renal Cell Carcinoma (a kidney cancer): 8 people, 25.00%
  8. Fever: 8 people, 25.00%
  9. Dyspnea (difficult or laboured breathing): 8 people, 25.00%
  10. Bone Density Decreased: 5 people, 15.62%

* Approximation only. Some reports may have incomplete information.

Do you take Ambien and have Keratitis?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ambien:

Keratitis treatments and more:

How severe was Keratitis and when was it recovered:

Expand to all the drugs that have ingredients of zolpidem tartrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Keratitis:

Browse all the conditions that are associated with Keratitis:

Drugs similar to Ambien and Keratitis :

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Ambien) and Ambien (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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