Ambisome and Interstitial nephritis - a phase IV clinical study of FDA data

Summary:

Interstitial nephritis is reported as a side effect among people who take Ambisome (amphotericin b), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vancomycin, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Interstitial nephritis when taking Ambisome. It is created by eHealthMe based on reports of 7,928 people who have side effects when taking Ambisome from the FDA, and is updated regularly.

What is Ambisome?

Ambisome has active ingredients of amphotericin b. eHealthMe is studying from 7,934 Ambisome users. Check the latest studies of Ambisome.

What is Interstitial nephritis?

Interstitial nephritis (inflammation of the kidney) is found to be associated with 1,090 drugs and 1,567 conditions by eHealthMe. Check the latest studies of Interstitial nephritis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

7,928 people reported to have side effects when taking Ambisome.
Among them, 12 people (0.15%) have Interstitial nephritis.

Could Ambisome cause Interstitial nephritis?

Among these 12 people:

How long have people been on Ambisome when they have Interstitial nephritis? *

What is the gender of people who have Interstitial nephritis when taking Ambisome? *

female: 16.67 %
male: 83.33 %

What is the age of people who have Interstitial nephritis when taking Ambisome? *

What are other drugs people take besides Ambisome? *

What are other side effects people have besides Interstitial nephritis? *

Encephalopathy (functioning of the brain is affected by some agent or condition): 4 people, 33.33%
Renal Tubular Necrosis (death of kidney tubules): 3 people, 25.00%
Acute Kidney Failure: 3 people, 25.00%
Renal Impairment (severely reduced kidney function): 2 people, 16.67%
Diabetes: 2 people, 16.67%
Pancreatitis (inflammation of pancreas): 2 people, 16.67%
Blood Creatinine Increased: 2 people, 16.67%
Hypokalemia (low potassium): 2 people, 16.67%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 2 people, 16.67%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 16.67%

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 25.00%
Myeloid Leukaemia (a type of cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 16.67%
Lung Disorder (lung disease): 2 people, 16.67%
Fungal Infection: 1 person, 8.33%
Anal Fissure: 1 person, 8.33%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 1 person, 8.33%
Cytarabine Syndrome (due to high dose of cytarbine consists of fever, muscle ache, bone pain, occasional chest pain, rash): 1 person, 8.33%
Device Related Infection: 1 person, 8.33%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 1 person, 8.33%
Febrile Neutropenia (fever with reduced white blood cells): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Ambisome and have Interstitial nephritis?

- Check whether Interstitial nephritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ambisome:

Ambisome (7,934 reports)

Browse all side effects of Ambisome:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Interstitial nephritis:

Interstitial nephritis (1,090 drugs)

Browse all the conditions that are associated with Interstitial nephritis:

Interstitial nephritis (1,567 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amphotericin b (the active ingredients of Ambisome) and Ambisome (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.