Amicar and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Amicar (aminocaproic acid), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Trasylol, and have High blood cholesterol.

The study is created by eHealthMe based on reports of 1,317 people who have side effects when taking Amicar from the FDA, and is updated regularly.

What is Amicar?

Amicar has active ingredients of aminocaproic acid. eHealthMe is studying from 1,323 Amicar users. Check the latest studies of Amicar.

On Nov, 01, 2025

1,317 people reported to have side effects when taking Amicar.
Among them, 182 people (13.82%) died.

Among these 182 people:

How long have people been on Amicar when they died? *

What is the gender of people who died when taking Amicar? *

female: 33.52 %
male: 66.48 %

What is the age of people who died when taking Amicar? *

What are other drugs people take besides Amicar? *

What are other side effects people have before they died? *

Pain: 139 people, 76.37%
Stress And Anxiety: 130 people, 71.43%
Injury: 129 people, 70.88%
Acute Kidney Failure: 123 people, 67.58%
Fear: 111 people, 60.99%
Renal Injury (kidney injury): 110 people, 60.44%
Renal Impairment (severely reduced kidney function): 100 people, 54.95%
Emotional Distress: 91 people, 50.00%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 89 people, 48.90%
Multi-Organ Failure (multisystem organ failure): 86 people, 47.25%

What are the existing conditions these people have? *

High Blood Cholesterol: 17 people, 9.34%
Haemorrhage (bleeding): 15 people, 8.24%
Breast Cancer Metastatic: 14 people, 7.69%
Aortic Valve Incompetence: 14 people, 7.69%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 8 people, 4.40%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 3.30%
High Blood Pressure: 4 people, 2.20%
Decreased Ventricular Afterload (decreased tension or stress developed in the wall of the left ventricle during ejection): 4 people, 2.20%
Prostate Cancer: 3 people, 1.65%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 1.65%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amicar:

Amicar (1,323 reports)

Expand to all the drugs that have ingredients of aminocaproic acid:

Death and drugs with ingredients of aminocaproic acid (226 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Amicar side effects:

Browse all side effects of Amicar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Death:

Revlimid side effect: Death (26,599 reports)
Oxycontin side effect: Death (26,234 reports)
Eliquis side effect: Death (20,064 reports)
Percocet side effect: Death (18,245 reports)
Aspirin side effect: Death (17,506 reports)
Dilaudid side effect: Death (16,039 reports)
Duragesic side effect: Death (15,973 reports)
Prolia side effect: Death (15,556 reports)
Aranesp side effect: Death (15,538 reports)
Ms contin side effect: Death (14,956 reports)

Browse all the drugs that are associated with Death:

Death (3,190 drugs)

Common conditions associated with Death:

Multiple myeloma: 23,142 reports
Pain exacerbated: 20,012 reports
Pain: 19,371 reports
Pain relief: 18,934 reports
Acupuncture and pain: 17,984 reports
Plasma cell myeloma: 17,926 reports
Pulmonary arterial hypertension: 17,771 reports
Primary pulmonary hypertension: 16,747 reports
Myeloma - multiple: 15,037 reports
Sporadic primary pulmonary hypertension: 13,754 reports

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aminocaproic acid (the active ingredients of Amicar) and Amicar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.