Amicar and Primary sequestrum - a phase IV clinical study of FDA data

Summary:

Primary sequestrum is reported as a side effect among people who take Amicar (aminocaproic acid), especially for people who are male, 50-59 old, also take Lovenox, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Primary sequestrum when taking Amicar. It is created by eHealthMe based on reports of 1,317 people who have side effects when taking Amicar from the FDA, and is updated regularly.

What is Amicar?

Amicar has active ingredients of aminocaproic acid. eHealthMe is studying from 1,323 Amicar users. Check the latest studies of Amicar.

What is Primary sequestrum?

Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone) is found to be associated with 608 drugs and 322 conditions by eHealthMe. Check the latest studies of Primary sequestrum.

On Oct, 15, 2025

1,317 people reported to have side effects when taking Amicar.
Among them, 13 people (0.99%) have Primary sequestrum.

Among these 13 people:

What is the gender of people who have Primary sequestrum when taking Amicar? *

female: 0.0 %
male: 100 %

What is the age of people who have Primary sequestrum when taking Amicar? *

What are other drugs people take besides Amicar? *

Zometa: 13 people, 100.00%
Metronidazole: 13 people, 100.00%
Vicodin Es: 13 people, 100.00%
Vicodin: 13 people, 100.00%
Amoxicillin: 13 people, 100.00%
Thalidomide: 13 people, 100.00%
Lovenox: 13 people, 100.00%
Chlorhexidine Gluconate: 12 people, 92.31%
Hydrocodone Bitartrate And Acetaminophen: 12 people, 92.31%
Ibuprofen: 12 people, 92.31%

What are other side effects people have besides Primary sequestrum? *

Joint Pain: 13 people, 100.00%
Rashes (redness): 13 people, 100.00%
Ventricular Hypertrophy (enlargement of ventricles (lower chambers) in the heart): 13 people, 100.00%
Intervertebral Disc Protrusion (spinal disc protrusion): 13 people, 100.00%
Injury: 13 people, 100.00%
Osteopenia (a condition where bone mineral density is lower than normal): 13 people, 100.00%
Heart Attack: 13 people, 100.00%
Pain: 13 people, 100.00%
Papilloma (small, noncancerous (benign) tumour): 13 people, 100.00%
Periodontal Disease (disease that attacks the gum and bone and around the teeth): 13 people, 100.00%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 13 people, 100.00%
Pain: 6 people, 46.15%

* Approximation only. Some reports may have incomplete information.

Do you take Amicar and have Primary sequestrum?

- Check whether Primary sequestrum is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amicar:

Amicar (1,323 reports)

Browse all side effects of Amicar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Primary sequestrum:

Primary sequestrum (608 drugs)

Browse all the conditions that are associated with Primary sequestrum:

Primary sequestrum (322 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aminocaproic acid (the active ingredients of Amicar) and Amicar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.