Amisulpride and Tardive dyskinesia - a phase IV clinical study of FDA data


We study 5,845 people who have side effects when taking Amisulpride. Tardive dyskinesia is found, especially among people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take Risperidone and have Schizophrenia.

The phase IV clinical study analyzes which people take Amisulpride and have Tardive dyskinesia. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 25, 2023

5,845 people reported to have side effects when taking Amisulpride.
Among them, 56 people (0.96%) have Tardive dyskinesia.

What is Amisulpride?

Amisulpride has active ingredients of amisulpride. Currently, eHealthMe is studying from 5,869 Amisulpride users.

What is Tardive dyskinesia?

Tardive dyskinesia (a disorder that involves involuntary movements) is found to be associated with 1,981 drugs and 1,262 conditions by eHealthMe. Currently, we are studying 49,416 people who have Tardive dyskinesia.

Number of Amisulpride and Tardive dyskinesia reports submitted per year:

Could Amisulpride cause Tardive dyskinesia?

Time on Amisulpride when people have Tardive dyskinesia *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Tardive dyskinesia when taking Amisulpride *:

  • female: 59.18 %
  • male: 40.82 %

Age of people who have Tardive dyskinesia when taking Amisulpride *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.44 %
  • 20-29: 21.95 %
  • 30-39: 12.2 %
  • 40-49: 21.95 %
  • 50-59: 17.07 %
  • 60+: 24.39 %

Common drugs people take besides Amisulpride *:

  1. Risperidone: 10 people, 17.86%
  2. Aripiprazole: 9 people, 16.07%
  3. Sertraline: 9 people, 16.07%
  4. Clozapine: 9 people, 16.07%
  5. Clozaril: 6 people, 10.71%
  6. Olanzapine: 6 people, 10.71%
  7. Haloperidol: 6 people, 10.71%
  8. Escitalopram: 4 people, 7.14%
  9. Lorazepam: 4 people, 7.14%
  10. Haldol: 4 people, 7.14%

Common side effects people have besides Tardive dyskinesia *:

  1. Movement - Uncontrolled Or Slow: 11 people, 19.64%
  2. Akathisia (a movement disorder characterized by a feeling of inner restlessness): 10 people, 17.86%
  3. Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 10 people, 17.86%
  4. Tremor (trembling or shaking movements in one or more parts of your body): 9 people, 16.07%
  5. Stress And Anxiety: 8 people, 14.29%
  6. Oculogyric Crisis (a spasmodic movement of the eyeballs into a fixed position due to medicine reaction): 7 people, 12.50%
  7. Salivary Hypersecretion (excess saliva secretion): 7 people, 12.50%
  8. Speech Disorder: 6 people, 10.71%
  9. Electrocardiogram Qt Prolonged: 6 people, 10.71%
  10. Depression: 6 people, 10.71%

Common conditions people have *:

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 19 people, 33.93%
  2. Depression: 13 people, 23.21%
  3. Psychotic Disorder: 6 people, 10.71%
  4. Bipolar Disorder (mood disorder): 3 people, 5.36%
  5. Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 2 people, 3.57%
  6. Parkinson's Disease: 2 people, 3.57%
  7. Stress And Anxiety: 1 person, 1.79%
  8. Muscle Rigidity (muscle stiffness): 1 person, 1.79%
  9. Incontinence (lack of moderation or self-control): 1 person, 1.79%
  10. High Blood Pressure: 1 person, 1.79%

* Approximation only. Some reports may have incomplete information.

Do you take Amisulpride and have Tardive dyskinesia?

Check whether Tardive dyskinesia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Tardive dyskinesia and when was it recovered:

Expand to all the drugs that have ingredients of amisulpride:

Alternative drugs to, pros and cons of Amisulpride:

Browse all side effects of Amisulpride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Tardive dyskinesia treatments and more:

Common drugs associated with Tardive dyskinesia:

All the drugs that are associated with Tardive dyskinesia:

Common conditions associated with Tardive dyskinesia:

All the conditions that are associated with Tardive dyskinesia:

How the study uses the data?

The study uses data from the FDA. It is based on amisulpride (the active ingredients of Amisulpride) and Amisulpride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: