Amitiza and Impaired work ability - a phase IV clinical study of FDA data

Summary:

Impaired work ability is reported as a side effect among people who take Amitiza (lubiprostone), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Zofran, and have Depression.

The phase IV clinical study analyzes which people have Impaired work ability when taking Amitiza. It is created by eHealthMe based on reports of 10,225 people who have side effects when taking Amitiza from the FDA, and is updated regularly.

What is Amitiza?

Amitiza has active ingredients of lubiprostone. It is often used in constipation. eHealthMe is studying from 10,567 Amitiza users. Check the latest studies of Amitiza.

What is Impaired work ability?

Impaired work ability is found to be associated with 1,011 drugs and 1,137 conditions by eHealthMe. Check the latest studies of Impaired work ability.

On Jul, 15, 2026

10,225 people reported to have side effects when taking Amitiza.
Among them, 20 people (0.2%) have Impaired work ability.

Could Amitiza cause Impaired work ability?

Among these 20 people:

How long have people been on Amitiza when they have Impaired work ability? *

What is the gender of people who have Impaired work ability when taking Amitiza? *

female: 63.16 %
male: 36.84 %

What is the age of people who have Impaired work ability when taking Amitiza? *

What are other drugs people take besides Amitiza? *

What are other side effects people have besides Impaired work ability? *

Stress And Anxiety: 7 people, 35.00%
Pain: 6 people, 30.00%
Headache (pain in head): 5 people, 25.00%
Suicidal Ideation: 5 people, 25.00%
Fatigue (feeling of tiredness): 5 people, 25.00%
Emotional Distress: 4 people, 20.00%
Secretion Discharge: 4 people, 20.00%
Muscle Spasms (muscle contraction): 4 people, 20.00%
Itching: 4 people, 20.00%
Hypophagia (reduced food intake): 4 people, 20.00%

What are the existing conditions these people have? *

Depression: 4 people, 20.00%
Hiv Infection: 3 people, 15.00%
Weight Abnormal: 2 people, 10.00%
Headache (pain in head): 2 people, 10.00%
Pain: 2 people, 10.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.00%
Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 1 person, 5.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 5.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Amitiza and have Impaired work ability?

- Check whether Impaired work ability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amitiza:

Amitiza (10,567 reports)

Browse all side effects of Amitiza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Impaired work ability:

Impaired work ability (1,011 drugs)

Browse all the conditions that are associated with Impaired work ability:

Impaired work ability (1,137 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lubiprostone (the active ingredients of Amitiza) and Amitiza (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.