Amphetamine and Depression - a phase IV clinical study of FDA data

Summary:

Depression is reported as a side effect among people who take Amphetamine (amphetamine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Baclofen, and have Ankylosing spondylitis.

The phase IV clinical study analyzes which people have Depression when taking Amphetamine. It is created by eHealthMe based on reports of 972 people who have side effects when taking Amphetamine from the FDA, and is updated regularly.

What is Amphetamine?

Amphetamine has active ingredients of amphetamine. eHealthMe is studying from 980 Amphetamine users. Check the latest studies of Amphetamine.

What is Depression?

Depression is found to be associated with 3,168 drugs and 4,126 conditions by eHealthMe. Check the latest studies of Depression.

On Jul, 21, 2026

972 people reported to have side effects when taking Amphetamine.
Among them, 12 people (1.23%) have Depression.

Among these 12 people:

How long have people been on Amphetamine when they have Depression? *

What is the gender of people who have Depression when taking Amphetamine? *

female: 40 %
male: 60 %

What is the age of people who have Depression when taking Amphetamine? *

What are other drugs people take besides Amphetamine? *

Hydrocodone: 4 people, 33.33%
Baclofen: 4 people, 33.33%
Zolpidem: 3 people, 25.00%
Carisoprodol: 3 people, 25.00%
Gabapentin: 3 people, 25.00%
Hydrocodone Bitartrate And Acetaminophen: 3 people, 25.00%
Lisinopril: 2 people, 16.67%
Lorazepam: 2 people, 16.67%
Melatonin: 2 people, 16.67%
Meprobamate: 2 people, 16.67%

What are other side effects people have besides Depression? *

Fatigue (feeling of tiredness): 6 people, 50.00%
Stress And Anxiety: 6 people, 50.00%
Pain: 4 people, 33.33%
Weakness: 4 people, 33.33%
Headache (pain in head): 4 people, 33.33%
Panic Disorder: 3 people, 25.00%
Rashes (redness): 3 people, 25.00%
Feeling Abnormal: 3 people, 25.00%
Memory Loss: 3 people, 25.00%
Limb Injury: 3 people, 25.00%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 16.67%
Insomnia (sleeplessness): 2 people, 16.67%
Drowsiness: 2 people, 16.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 16.67%
Back Pain: 2 people, 16.67%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 16.67%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 16.67%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 8.33%
Swelling: 1 person, 8.33%
Swallowing Difficulty: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Amphetamine and have Depression?

- Check whether Depression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amphetamine:

Amphetamine (980 reports)

Depression treatments and more:

Depression (652,144 reports)

Browse all side effects of Amphetamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Depression:

Depression (3,168 drugs)

Browse all the conditions that are associated with Depression:

Depression (4,126 conditions)

Related publications that referenced our studies

Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .
Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on amphetamine (the active ingredients of Amphetamine) and Amphetamine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.