Ampyra and Clostridium difficile colitis - a phase IV clinical study of FDA data

Summary:

Clostridium difficile colitis is reported as a side effect among people who take Ampyra (dalfampridine), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Zyrtec, and have Gait disturbance.

The phase IV clinical study analyzes which people have Clostridium difficile colitis when taking Ampyra. It is created by eHealthMe based on reports of 76,998 people who have side effects when taking Ampyra from the FDA, and is updated regularly.

What is Ampyra?

Ampyra has active ingredients of dalfampridine. It is often used in multiple sclerosis. eHealthMe is studying from 77,145 Ampyra users. Check the latest studies of Ampyra.

What is Clostridium difficile colitis?

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) is found to be associated with 1,042 drugs and 1,783 conditions by eHealthMe. Check the latest studies of Clostridium difficile colitis.

On Jul, 27, 2026

76,998 people reported to have side effects when taking Ampyra.
Among them, 26 people (0.03%) have Clostridium difficile colitis.

Could Ampyra cause Clostridium difficile colitis?

Among these 26 people:

How long have people been on Ampyra when they have Clostridium difficile colitis? *

What is the gender of people who have Clostridium difficile colitis when taking Ampyra? *

female: 72 %
male: 28 %

What is the age of people who have Clostridium difficile colitis when taking Ampyra? *

What are other drugs people take besides Ampyra? *

What are other side effects people have besides Clostridium difficile colitis? *

Urinary Tract Infection: 10 people, 38.46%
Weakness: 6 people, 23.08%
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 6 people, 23.08%
Fall: 6 people, 23.08%
Diarrhea: 5 people, 19.23%
Fever: 4 people, 15.38%
Urinary Tract Infection Bacterial: 4 people, 15.38%
Memory Loss: 4 people, 15.38%
Pharyngitis Streptococcal (inflammation of the pharynx caused by infection from. streptococcus): 4 people, 15.38%
Fungal Skin Infection: 4 people, 15.38%

What are the existing conditions these people have? *

Gait Disturbance: 12 people, 46.15%
Insomnia (sleeplessness): 9 people, 34.62%
Fever: 6 people, 23.08%
Urinary Tract Infection: 6 people, 23.08%
Constipation: 6 people, 23.08%
Carotid Artery Disease: 4 people, 15.38%
Pain: 4 people, 15.38%
Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 4 people, 15.38%
Gout (uric acid crystals building up in the body): 4 people, 15.38%
Muscle Spasms (muscle contraction): 4 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Ampyra and have Clostridium difficile colitis?

- Check whether Clostridium difficile colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ampyra:

Ampyra (77,145 reports)

Browse all side effects of Ampyra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,042 drugs)

Browse all the conditions that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,783 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dalfampridine (the active ingredients of Ampyra) and Ampyra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.