Amrix and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Amrix (cyclobenzaprine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Cymbalta, and have Pain.

The phase IV clinical study analyzes which people have Constipation when taking Amrix. It is created by eHealthMe based on reports of 898 people who have side effects when taking Amrix from the FDA, and is updated regularly.

What is Amrix?

Amrix has active ingredients of cyclobenzaprine hydrochloride. It is often used in back pain. eHealthMe is studying from 1,130 Amrix users. Check the latest studies of Amrix.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,586 conditions by eHealthMe. Check the latest studies of Constipation.

On Nov, 02, 2025

898 people reported to have side effects when taking Amrix.
Among them, 14 people (1.56%) have Constipation.

Among these 14 people:

How long have people been on Amrix when they have Constipation? *

What is the gender of people who have Constipation when taking Amrix? *

female: 78.57 %
male: 21.43 %

What is the age of people who have Constipation when taking Amrix? *

What are other drugs people take besides Amrix? *

What are other side effects people have besides Constipation? *

Fatigue (feeling of tiredness): 6 people, 42.86%
Abdominal Pain Upper: 4 people, 28.57%
Dizziness: 4 people, 28.57%
Vision Blurred: 3 people, 21.43%
Pain: 3 people, 21.43%
Memory Loss: 3 people, 21.43%
Headache (pain in head): 2 people, 14.29%
Nausea (feeling of having an urge to vomit): 2 people, 14.29%
Muscle Spasms (muscle contraction): 2 people, 14.29%
Hyperhidrosis (abnormally increased sweating): 2 people, 14.29%

What are the existing conditions these people have? *

High Blood Cholesterol: 3 people, 21.43%
Muscle Spasms (muscle contraction): 3 people, 21.43%
Pain: 3 people, 21.43%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 14.29%
Depression: 2 people, 14.29%
Diabetes: 1 person, 7.14%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 7.14%
Fatigue (feeling of tiredness): 1 person, 7.14%
Dyspnea (difficult or laboured breathing): 1 person, 7.14%
Drowsiness: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Amrix and have Constipation?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amrix:

Amrix (1,130 reports)

Constipation treatments and more:

Constipation (337,863 reports)

Browse all side effects of Amrix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,004 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,586 conditions)

Drugs similar to Amrix and Constipation :

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride (the active ingredients of Amrix) and Amrix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.