Apixaban and Hypernatraemia - a phase IV clinical study of FDA data

Summary:

Hypernatraemia is reported as a side effect among people who take Apixaban (apixaban), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Amlodipine, and have Stroke.

The phase IV clinical study analyzes which people have Hypernatraemia when taking Apixaban. It is created by eHealthMe based on reports of 60,044 people who have side effects when taking Apixaban from the FDA, and is updated regularly.

What is Apixaban?

Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,351 Apixaban users. Check the latest studies of Apixaban.

What is Hypernatraemia?

Hypernatraemia (an abnormally high plasma concentration of sodium ions) is found to be associated with 645 drugs and 807 conditions by eHealthMe. Check the latest studies of Hypernatraemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

60,044 people reported to have side effects when taking Apixaban.
Among them, 20 people (0.03%) have Hypernatraemia.

Among these 20 people:

How long have people been on Apixaban when they have Hypernatraemia? *

What is the gender of people who have Hypernatraemia when taking Apixaban? *

female: 25 %
male: 75 %

What is the age of people who have Hypernatraemia when taking Apixaban? *

What are other drugs people take besides Apixaban? *

Pantoprazole: 5 people, 25.00%
Amlodipine: 5 people, 25.00%
Furosemide: 4 people, 20.00%
Samsca: 4 people, 20.00%
Bisoprolol Fumarate: 3 people, 15.00%
Calcium Carbonate: 2 people, 10.00%
Crestor: 2 people, 10.00%
Rosuvastatin Calcium: 2 people, 10.00%
Enalapril Maleate: 2 people, 10.00%
Esomeprazole Magnesium: 2 people, 10.00%

What are other side effects people have besides Hypernatraemia? *

Dehydration (dryness resulting from the removal of water): 6 people, 30.00%
Fever: 3 people, 15.00%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 3 people, 15.00%
Delirium (wild excitement): 3 people, 15.00%
Joint Ankylosis (a stiffness of a joint due to abnormal adhesion and rigidity of the bones of the joint): 2 people, 10.00%
Histiocytosis Haematophagic: 2 people, 10.00%
Fall: 2 people, 10.00%
Pneumonia: 2 people, 10.00%
Hypokalemia (low potassium): 2 people, 10.00%
Bacterial Sepsis: 2 people, 10.00%

What are the existing conditions these people have? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 20.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 15.00%
Cardiac Failure: 3 people, 15.00%
Oesophageal Cancer Metastatic (cancer of oesophagues spreads to other part): 3 people, 15.00%
High Blood Pressure: 3 people, 15.00%
Urinary Tract Infection: 2 people, 10.00%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 2 people, 10.00%
Neoplasm Malignant (cancer tumour): 2 people, 10.00%
Cardiac Failure Chronic: 2 people, 10.00%
Left Ventricular Failure (left ventricle fails to contract forcefully): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Apixaban and have Hypernatraemia?

- Check whether Hypernatraemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Apixaban:

Apixaban (60,351 reports)

Hypernatraemia treatments and more:

Hypernatraemia (6,339 reports)

Browse all side effects of Apixaban:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypernatraemia:

Hypernatraemia (645 drugs)

Browse all the conditions that are associated with Hypernatraemia:

Hypernatraemia (807 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on apixaban (the active ingredients of Apixaban) and Apixaban (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.