Apokyn and Heart attack - a phase IV clinical study of FDA data

Summary:

Heart attack is reported as a side effect among people who take Apokyn (apomorphine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Carbidopa And Levodopa, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Heart attack when taking Apokyn. It is created by eHealthMe based on reports of 5,279 people who have side effects when taking Apokyn from the FDA, and is updated regularly.

What is Apokyn?

Apokyn has active ingredients of apomorphine hydrochloride. eHealthMe is studying from 5,284 Apokyn users. Check the latest studies of Apokyn.

What is Heart attack?

Heart attack is found to be associated with 2,475 drugs and 3,298 conditions by eHealthMe. Check the latest studies of Heart attack.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 06, 2026

5,279 people reported to have side effects when taking Apokyn.
Among them, 33 people (0.63%) have Heart attack.

Among these 33 people:

How long have people been on Apokyn when they have Heart attack? *

What is the gender of people who have Heart attack when taking Apokyn? *

female: 18.18 %
male: 81.82 %

What is the age of people who have Heart attack when taking Apokyn? *

What are other drugs people take besides Apokyn? *

Carbidopa And Levodopa: 5 people, 15.15%
Nuplazid: 4 people, 12.12%
Xanax: 4 people, 12.12%
Prozac: 4 people, 12.12%
Lisinopril: 3 people, 9.09%
Sinemet: 3 people, 9.09%
Neupro: 3 people, 9.09%
Flomax: 3 people, 9.09%
Levothyroxine Sodium: 2 people, 6.06%
Mirapex: 2 people, 6.06%

What are other side effects people have besides Heart attack? *

Pneumonia: 5 people, 15.15%
Loss Of Consciousness: 4 people, 12.12%
Drowsiness: 4 people, 12.12%
Muscle Rigidity (muscle stiffness): 4 people, 12.12%
Dyspnea (difficult or laboured breathing): 4 people, 12.12%
Dyskinesia (abnormality or impairment of voluntary movement): 4 people, 12.12%
Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 12.12%
Cardiac Failure Congestive: 3 people, 9.09%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 9.09%
Nausea (feeling of having an urge to vomit): 2 people, 6.06%

What are the existing conditions these people have? *

Parkinson's Disease: 28 people, 84.85%
Hallucinations (sensations that appear real but are created by your mind): 2 people, 6.06%
Delusion (a false belief or opinion): 2 people, 6.06%
Urinary Retention (the inability to completely or partially empty the bladder): 1 person, 3.03%
Stress And Anxiety: 1 person, 3.03%
Prostatomegaly (enlargement of the prostate): 1 person, 3.03%
Pain: 1 person, 3.03%
High Blood Pressure: 1 person, 3.03%
High Blood Cholesterol: 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Apokyn and have Heart attack?

- Check whether Heart attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Apokyn:

Apokyn (5,284 reports)

Heart attack treatments and more:

Heart attack (266,145 reports)

Browse all side effects of Apokyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart attack:

Heart attack (2,475 drugs)

Browse all the conditions that are associated with Heart attack:

Heart attack (3,298 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on apomorphine hydrochloride (the active ingredients of Apokyn) and Apokyn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.