Apokyn and Injection site haemorrhage - a phase IV clinical study of FDA data

Summary:

Injection site haemorrhage is reported as a side effect among people who take Apokyn (apomorphine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Rytary, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Injection site haemorrhage when taking Apokyn. It is created by eHealthMe based on reports of 5,279 people who have side effects when taking Apokyn from the FDA, and is updated regularly.

What is Apokyn?

Apokyn has active ingredients of apomorphine hydrochloride. eHealthMe is studying from 5,284 Apokyn users. Check the latest studies of Apokyn.

What is Injection site haemorrhage?

Injection site haemorrhage (bleeding from injection site) is found to be associated with 1,114 drugs and 1,134 conditions by eHealthMe. Check the latest studies of Injection site haemorrhage.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

5,279 people reported to have side effects when taking Apokyn.
Among them, 30 people (0.57%) have Injection site haemorrhage.

Could Apokyn cause Injection site haemorrhage?

Among these 30 people:

How long have people been on Apokyn when they have Injection site haemorrhage? *

What is the gender of people who have Injection site haemorrhage when taking Apokyn? *

female: 40 %
male: 60 %

What is the age of people who have Injection site haemorrhage when taking Apokyn? *

What are other drugs people take besides Apokyn? *

What are other side effects people have besides Injection site haemorrhage? *

Injection Site Pain: 10 people, 33.33%
Injection Site Bruising: 9 people, 30.00%
Nausea (feeling of having an urge to vomit): 9 people, 30.00%
Drowsiness: 6 people, 20.00%
Head Injury: 5 people, 16.67%
Muscle Aches (muscle pain): 4 people, 13.33%
Dizziness: 4 people, 13.33%
Injection Site Erythema (redness at injection site): 3 people, 10.00%
Weakness: 3 people, 10.00%
Fall: 3 people, 10.00%

What are the existing conditions these people have? *

Parkinson's Disease: 25 people, 83.33%
Pain: 1 person, 3.33%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 1 person, 3.33%
Lymphoma (cancer that begins in immune system cells): 1 person, 3.33%
Hypersensitivity: 1 person, 3.33%
High Blood Pressure: 1 person, 3.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.33%
Dyspnea (difficult or laboured breathing): 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Apokyn and have Injection site haemorrhage?

- Check whether Injection site haemorrhage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Apokyn:

Apokyn (5,284 reports)

Browse all side effects of Apokyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site haemorrhage:

Injection site haemorrhage (1,114 drugs)

Browse all the conditions that are associated with Injection site haemorrhage:

Injection site haemorrhage (1,134 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on apomorphine hydrochloride (the active ingredients of Apokyn) and Apokyn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.