Aprepitant and Heart attack - a phase IV clinical study of FDA data

Summary:

Heart attack is reported as a side effect among people who take Aprepitant (aprepitant), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Carboplatin, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Heart attack when taking Aprepitant. It is created by eHealthMe based on reports of 6,989 people who have side effects when taking Aprepitant from the FDA, and is updated regularly.

What is Aprepitant?

Aprepitant has active ingredients of aprepitant. eHealthMe is studying from 6,992 Aprepitant users. Check the latest studies of Aprepitant.

What is Heart attack?

Heart attack is found to be associated with 2,514 drugs and 3,289 conditions by eHealthMe. Check the latest studies of Heart attack.

On Apr, 24, 2026

6,989 people reported to have side effects when taking Aprepitant.
Among them, 19 people (0.27%) have Heart attack.

Among these 19 people:

How long have people been on Aprepitant when they have Heart attack? *

What is the gender of people who have Heart attack when taking Aprepitant? *

female: 29.41 %
male: 70.59 %

What is the age of people who have Heart attack when taking Aprepitant? *

What are other drugs people take besides Aprepitant? *

What are other side effects people have besides Heart attack? *

Arrhythmias (irregular heartbeat): 2 people, 10.53%
Cardiac Arrest: 2 people, 10.53%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 2 people, 10.53%
Cardiogenic Shock (inadequate circulation of blood): 2 people, 10.53%
Diarrhea: 2 people, 10.53%
Ventricular Fibrillation (abnormally irregular heart rhythm): 2 people, 10.53%
Weakness: 1 person, 5.26%
Fatigue (feeling of tiredness): 1 person, 5.26%
Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 1 person, 5.26%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.26%

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 5 people, 26.32%
Anaemia (lack of blood): 3 people, 15.79%
Type 2 Diabetes: 2 people, 10.53%
Breast Cancer: 2 people, 10.53%
Depression: 2 people, 10.53%
Diarrhea: 2 people, 10.53%
Dyspnea (difficult or laboured breathing): 2 people, 10.53%
Fever: 2 people, 10.53%
Gastric Cancer (stomach cancer): 2 people, 10.53%
Heart Rate Irregular: 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Aprepitant and have Heart attack?

- Check whether Heart attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aprepitant:

Aprepitant (6,992 reports)

Heart attack treatments and more:

Heart attack (266,142 reports)

Browse all side effects of Aprepitant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart attack:

Heart attack (2,514 drugs)

Browse all the conditions that are associated with Heart attack:

Heart attack (3,289 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aprepitant (the active ingredients of Aprepitant) and Aprepitant (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.