Aprepitant and Proctalgia - a phase IV clinical study of FDA data

Summary:

Proctalgia is reported as a side effect among people who take Aprepitant (aprepitant), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Pantoprazole, and have Bone marrow conditioning regimen.

The phase IV clinical study analyzes which people have Proctalgia when taking Aprepitant. It is created by eHealthMe based on reports of 6,989 people who have side effects when taking Aprepitant from the FDA, and is updated regularly.

What is Aprepitant?

Aprepitant has active ingredients of aprepitant. eHealthMe is studying from 6,992 Aprepitant users. Check the latest studies of Aprepitant.

What is Proctalgia?

Proctalgia (pain in the rectum) is found to be associated with 834 drugs and 761 conditions by eHealthMe. Check the latest studies of Proctalgia.

On Sep, 21, 2025

6,989 people reported to have side effects when taking Aprepitant.
Among them, 7 people (0.1%) have Proctalgia.

Among these 7 people:

How long have people been on Aprepitant when they have Proctalgia? *

What is the gender of people who have Proctalgia when taking Aprepitant? *

female: 100 %
male: 0.0 %

What is the age of people who have Proctalgia when taking Aprepitant? *

What are other drugs people take besides Aprepitant? *

Pantoprazole: 5 people, 71.43%
Ondansetron: 4 people, 57.14%
Ramelteon: 1 person, 14.29%
Paclitaxel: 1 person, 14.29%
Ondansetron Hydrochloride: 1 person, 14.29%
Olanzapine: 1 person, 14.29%
Micafungin: 1 person, 14.29%
Metoclopramide Hydrochloride: 1 person, 14.29%
Levothyroxine Sodium: 1 person, 14.29%
Esomeprazole Magnesium: 1 person, 14.29%

What are other side effects people have besides Proctalgia? *

Diarrhea: 7 people, 100.00%
Leukopenia (less number of white blood cells in blood): 4 people, 57.14%
Fatigue (feeling of tiredness): 4 people, 57.14%
Dehydration (dryness resulting from the removal of water): 4 people, 57.14%
Anaemia (lack of blood): 4 people, 57.14%
Staphylococcal Infection (an infection with staphylococcus bacteria): 3 people, 42.86%
Urinary Tract Infection: 2 people, 28.57%
Staphylococcal Sepsis (blood infection by an infection with staphylococcus bacteria): 2 people, 28.57%
Oral Pain: 2 people, 28.57%
Nausea And Vomiting: 2 people, 28.57%

What are the existing conditions these people have? *

Diarrhea: 2 people, 28.57%
Constipation: 2 people, 28.57%
Bone Marrow Conditioning Regimen: 2 people, 28.57%
Rectal Cancer (cancer of rectum): 1 person, 14.29%
Neuroendocrine Carcinoma (cancer tumour that arise from cells of the endocrine (hormonal) and nervous systems): 1 person, 14.29%
Metastases To Liver (cancer spreads to liver): 1 person, 14.29%
Breast Cancer: 1 person, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Aprepitant and have Proctalgia?

- Check whether Proctalgia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aprepitant:

Aprepitant (6,992 reports)

Proctalgia treatments and more:

Proctalgia (9,250 reports)

Browse all side effects of Aprepitant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Proctalgia:

Proctalgia (834 drugs)

Browse all the conditions that are associated with Proctalgia:

Proctalgia (761 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aprepitant (the active ingredients of Aprepitant) and Aprepitant (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.