Aprepitant and Under active thyroid - a phase IV clinical study of FDA data

Summary:

Under active thyroid is reported as a side effect among people who take Aprepitant (aprepitant), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Carboplatin, and have Bladder cancer stage iv.

The phase IV clinical study analyzes which people have Under active thyroid when taking Aprepitant. It is created by eHealthMe based on reports of 6,989 people who have side effects when taking Aprepitant from the FDA, and is updated regularly.

What is Aprepitant?

Aprepitant has active ingredients of aprepitant. eHealthMe is studying from 6,992 Aprepitant users. Check the latest studies of Aprepitant.

What is Under active thyroid?

Under active thyroid is found to be associated with 2,766 drugs and 2,631 conditions by eHealthMe. Check the latest studies of Under active thyroid.

On Feb, 01, 2026

6,989 people reported to have side effects when taking Aprepitant.
Among them, 13 people (0.19%) have Under active thyroid.

Could Aprepitant cause Under active thyroid?

Among these 13 people:

How long have people been on Aprepitant when they have Under active thyroid? *

What is the gender of people who have Under active thyroid when taking Aprepitant? *

female: 50 %
male: 50 %

What is the age of people who have Under active thyroid when taking Aprepitant? *

What are other drugs people take besides Aprepitant? *

Carboplatin: 6 people, 46.15%
Magnesium Oxide: 4 people, 30.77%
Zolpidem Tartrate: 3 people, 23.08%
Imfinzi: 3 people, 23.08%
Dexamethasone Sodium Phosphate: 3 people, 23.08%
Ezetimibe: 2 people, 15.38%
Lomotil: 2 people, 15.38%
Lasix: 2 people, 15.38%
Yervoy: 2 people, 15.38%
Humalog: 2 people, 15.38%

What are other side effects people have besides Under active thyroid? *

Diarrhea: 6 people, 46.15%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 23.08%
Pain: 3 people, 23.08%
Chest Pain: 3 people, 23.08%
Malignant Neoplasm Progression (cancer tumour came back): 3 people, 23.08%
Lung Infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 2 people, 15.38%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 2 people, 15.38%
Dyspnea (difficult or laboured breathing): 2 people, 15.38%
Disease Progression: 2 people, 15.38%
Blood Urine Present: 2 people, 15.38%

What are the existing conditions these people have? *

Thymic Cancer Metastatic: 2 people, 15.38%
Pain: 2 people, 15.38%
Lung Cancer - Small Cell (lung cancer): 2 people, 15.38%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 15.38%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 15.38%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 15.38%
Diabetes: 2 people, 15.38%
Constipation: 2 people, 15.38%
Bladder Cancer Stage Iv: 2 people, 15.38%
Peripheral Sensory Neuropathy (damage to one or more of your peripheral nerves): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Aprepitant and have Under active thyroid?

- Check whether Under active thyroid is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aprepitant:

Aprepitant (6,992 reports)

Browse all side effects of Aprepitant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Under active thyroid:

Under active thyroid (2,766 drugs)

Browse all the conditions that are associated with Under active thyroid:

Under active thyroid (2,631 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aprepitant (the active ingredients of Aprepitant) and Aprepitant (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.