Aptiom and Insomnia - a phase IV clinical study of FDA data

Summary:

Insomnia is reported as a side effect among people who take Aptiom (eslicarbazepine acetate), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Keppra, and have Seizures.

The phase IV clinical study analyzes which people have Insomnia when taking Aptiom. It is created by eHealthMe based on reports of 2,380 people who have side effects when taking Aptiom from the FDA, and is updated regularly.

What is Aptiom?

Aptiom has active ingredients of eslicarbazepine acetate. eHealthMe is studying from 2,404 Aptiom users. Check the latest studies of Aptiom.

What is Insomnia?

Insomnia (sleeplessness) is found to be associated with 3,115 drugs and 5,175 conditions by eHealthMe. Check the latest studies of Insomnia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 10, 2026

2,380 people reported to have side effects when taking Aptiom.
Among them, 60 people (2.52%) have Insomnia.

Among these 60 people:

How long have people been on Aptiom when they have Insomnia? *

What is the gender of people who have Insomnia when taking Aptiom? *

female: 36.96 %
male: 63.04 %

What is the age of people who have Insomnia when taking Aptiom? *

What are other drugs people take besides Aptiom? *

What are other side effects people have besides Insomnia? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 30 people, 50.00%
Drowsiness: 14 people, 23.33%
Memory Loss: 14 people, 23.33%
Fatigue (feeling of tiredness): 13 people, 21.67%
Dizziness: 12 people, 20.00%
Fall: 10 people, 16.67%
Balance Disorder: 10 people, 16.67%
Epileptic Aura: 9 people, 15.00%
Weakness: 9 people, 15.00%
Agitation (state of anxiety or nervous excitement): 9 people, 15.00%

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 24 people, 40.00%
Partial Seizures (seizures which affect only a part of the brain at onset): 15 people, 25.00%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 11 people, 18.33%
Prostate Cancer: 2 people, 3.33%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 3.33%
Parkinson's Disease: 2 people, 3.33%
Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 3.33%
Localised Infection (infection at the single location): 2 people, 3.33%
Fatigue (feeling of tiredness): 2 people, 3.33%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 1.67%

* Approximation only. Some reports may have incomplete information.

Do you take Aptiom and have Insomnia?

- Check whether Insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aptiom:

Aptiom (2,404 reports)

Insomnia treatments and more:

Insomnia (438,087 reports)

Browse all side effects of Aptiom:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia:

Insomnia (3,115 drugs)

Browse all the conditions that are associated with Insomnia:

Insomnia (5,175 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on eslicarbazepine acetate (the active ingredients of Aptiom) and Aptiom (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.