Arava and Aortic bruit - a phase IV clinical study of FDA data

Summary:

Aortic bruit is reported as a side effect among people who take Arava (leflunomide), especially for people who are male, 40-49 old, also take Enbrel,.

The phase IV clinical study analyzes which people have Aortic bruit when taking Arava. It is created by eHealthMe based on reports of 75,674 people who have side effects when taking Arava from the FDA, and is updated regularly.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 76,040 Arava users. Check the latest studies of Arava.

What is Aortic bruit?

Aortic bruit (unusual sound that blood makes when it rushes past an obstruction in aortic artery) is found to be associated with 38 drugs and 94 conditions by eHealthMe. Check the latest studies of Aortic bruit.

On Jul, 15, 2026

75,674 people reported to have side effects when taking Arava.
Among them, 28 people (0.04%) have Aortic bruit.

Among these 28 people:

What is the gender of people who have Aortic bruit when taking Arava? *

female: 0.0 %
male: 100 %

What is the age of people who have Aortic bruit when taking Arava? *

What are other drugs people take besides Arava? *

What are other side effects people have besides Aortic bruit? *

Wrist Deformity: 28 people, 100.00%
Stress And Anxiety: 28 people, 100.00%
Skin Exfoliation (removal of the oldest dead skin cells): 28 people, 100.00%
Nail Disorder (disease of nail): 28 people, 100.00%
Mobility Decreased (ability to move is reduced): 28 people, 100.00%
Kidney Stones: 28 people, 100.00%
High Blood Pressure: 28 people, 100.00%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 28 people, 100.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 28 people, 100.00%
Drug Ineffective: 28 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Arava and have Aortic bruit?

- Check whether Aortic bruit is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Arava:

Arava (76,040 reports)

Aortic bruit treatments and more:

Aortic bruit (163 reports)

Browse all side effects of Arava:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aortic bruit:

Aortic bruit (38 drugs)

Browse all the conditions that are associated with Aortic bruit:

Aortic bruit (94 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on leflunomide (the active ingredients of Arava) and Arava (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.