Arava and Blood count abnormal - a phase IV clinical study of FDA data

Summary:

Blood count abnormal is reported as a side effect among people who take Arava (leflunomide), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Plaquenil, and have Neuropathy peripheral.

The phase IV clinical study analyzes which people have Blood count abnormal when taking Arava. It is created by eHealthMe based on reports of 75,674 people who have side effects when taking Arava from the FDA, and is updated regularly.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 76,039 Arava users. Check the latest studies of Arava.

What is Blood count abnormal?

Blood count abnormal is found to be associated with 903 drugs and 701 conditions by eHealthMe. Check the latest studies of Blood count abnormal.



On Jan, 30, 2026

75,674 people reported to have side effects when taking Arava.
Among them, 33 people (0.04%) have Blood count abnormal.

Could Arava cause Blood count abnormal?

Among these 33 people:

How long have people been on Arava when they have Blood count abnormal? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 16.67 %
  • 1 - 2 years: 50.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 33.33 %
  • 10+ years: 0.0 %

What is the gender of people who have Blood count abnormal when taking Arava? *

  • female: 80 %
  • male: 20 %

What is the age of people who have Blood count abnormal when taking Arava? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 28.57 %
  • 60+: 71.43 %

What are other drugs people take besides Arava? *

  1. Plaquenil: 13 people, 39.39%
  2. Enbrel: 11 people, 33.33%
  3. Cymbalta: 6 people, 18.18%
  4. Premarin: 6 people, 18.18%
  5. Humira: 6 people, 18.18%
  6. Magnesium Glycinate: 6 people, 18.18%
  7. Diclofenac: 6 people, 18.18%
  8. Actemra: 5 people, 15.15%
  9. Krill Oil: 5 people, 15.15%
  10. Actonel: 5 people, 15.15%

What are other side effects people have besides Blood count abnormal? *

  1. Pain: 10 people, 30.30%
  2. Drug Ineffective: 10 people, 30.30%
  3. Pain In Extremity: 8 people, 24.24%
  4. Infusion Related Reaction: 8 people, 24.24%
  5. Thrombocytopenia (decrease of platelets in blood): 8 people, 24.24%
  6. Dental Caries: 7 people, 21.21%
  7. Effusion (an escape of fluid into a body cavity): 6 people, 18.18%
  8. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 6 people, 18.18%
  9. Rib Fracture: 6 people, 18.18%
  10. Conjunctivitis (pink eye): 6 people, 18.18%

What are the existing conditions these people have? *

  1. Neuropathy Peripheral (surface nerve damage): 3 people, 9.09%
  2. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 3.03%
  3. Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 3.03%
  4. Osteoporosis (bones weak and more likely to break): 1 person, 3.03%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 3.03%
  6. High Blood Pressure: 1 person, 3.03%
  7. High Blood Cholesterol: 1 person, 3.03%
  8. Bladder Spasm: 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Arava and have Blood count abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Arava:

Blood count abnormal treatments and more:

How severe was Blood count abnormal and when was it recovered:

Expand to all the drugs that have ingredients of leflunomide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Arava:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blood count abnormal:

Browse all the conditions that are associated with Blood count abnormal:

Drugs similar to Arava and Blood count abnormal :


How the study uses the data?

The study uses data from the FDA. It is based on leflunomide (the active ingredients of Arava) and Arava (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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