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Arava and Monocyte count decreased - a phase IV clinical study of FDA data

Summary:

Monocyte count decreased is reported as a side effect among people who take Arava (leflunomide), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Synthroid, and have Asthma.

The phase IV clinical study analyzes which people have Monocyte count decreased when taking Arava. It is created by eHealthMe based on reports of 75,674 people who have side effects when taking Arava from the FDA, and is updated regularly.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 76,040 Arava users. Check the latest studies of Arava.

What is Monocyte count decreased?

Monocyte count decreased is found to be associated with 312 drugs and 393 conditions by eHealthMe. Check the latest studies of Monocyte count decreased.

On Jul, 20, 2026

75,674 people reported to have side effects when taking Arava.
Among them, 11 people (0.01%) have Monocyte count decreased.

Could Arava cause Monocyte count decreased?

Among these 11 people:

How long have people been on Arava when they have Monocyte count decreased? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Monocyte count decreased when taking Arava? *

  • female: 87.5 %
  • male: 12.5 %

What is the age of people who have Monocyte count decreased when taking Arava? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 12.5 %
  • 40-49: 62.5 %
  • 50-59: 0.0 %
  • 60+: 25.0 %

What are other drugs people take besides Arava? *

  1. Actemra: 6 people, 54.55%
  2. Amlodipine: 6 people, 54.55%
  3. Synthroid: 6 people, 54.55%
  4. Lipitor: 5 people, 45.45%
  5. Orencia: 5 people, 45.45%
  6. Methotrexate: 4 people, 36.36%
  7. Methylprednisolone: 3 people, 27.27%
  8. Metformin: 2 people, 18.18%
  9. Benadryl: 2 people, 18.18%
  10. Diphenhydramine Hydrochloride: 2 people, 18.18%

What are other side effects people have besides Monocyte count decreased? *

  1. White Blood Cell Count Decreased: 8 people, 72.73%
  2. Joint Pain: 8 people, 72.73%
  3. Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 7 people, 63.64%
  4. Pneumonia: 7 people, 63.64%
  5. Kidney Infection: 6 people, 54.55%
  6. Fever: 6 people, 54.55%
  7. Joint Swelling: 6 people, 54.55%
  8. Infusion Related Reaction: 6 people, 54.55%
  9. Hypersensitivity: 6 people, 54.55%
  10. High Blood Pressure: 6 people, 54.55%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 1 person, 9.09%
  2. Inflammation: 1 person, 9.09%
  3. Immunodeficiency Disorders: 1 person, 9.09%
  4. Asthma: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Arava and have Monocyte count decreased?

- Check whether Monocyte count decreased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Arava:

Monocyte count decreased treatments and more:

How severe was Monocyte count decreased and when was it recovered:

Expand to all the drugs that have ingredients of leflunomide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Arava:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Monocyte count decreased:

Browse all the conditions that are associated with Monocyte count decreased:

How the study uses the data?

The study uses data from the FDA. It is based on leflunomide (the active ingredients of Arava) and Arava (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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