Arava and Multiple injuries - a phase IV clinical study of FDA data

Summary:

Multiple injuries is reported as a side effect among people who take Arava (leflunomide), especially for people who are female, 60+ old, also take Prednisone, and have Heart rate irregular.

The phase IV clinical study analyzes which people have Multiple injuries when taking Arava. It is created by eHealthMe based on reports of 75,674 people who have side effects when taking Arava from the FDA, and is updated regularly.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 76,040 Arava users. Check the latest studies of Arava.

What is Multiple injuries?

Multiple injuries is found to be associated with 650 drugs and 486 conditions by eHealthMe. Check the latest studies of Multiple injuries.



On Jul, 09, 2026

75,674 people reported to have side effects when taking Arava.
Among them, 13 people (0.02%) have Multiple injuries.

Could Arava cause Multiple injuries?

Among these 13 people:

What is the gender of people who have Multiple injuries when taking Arava? *

  • female: 53.85 %
  • male: 46.15 %

What is the age of people who have Multiple injuries when taking Arava? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 50 %
  • 60+: 50 %

What are other drugs people take besides Arava? *

  1. Prednisone: 12 people, 92.31%
  2. Digoxin: 11 people, 84.62%
  3. Methotrexate: 11 people, 84.62%
  4. Nitroglycerin: 6 people, 46.15%
  5. Lasix: 6 people, 46.15%
  6. Lipitor: 5 people, 38.46%
  7. Mobic: 5 people, 38.46%
  8. Plaquenil: 5 people, 38.46%
  9. Lomotil: 5 people, 38.46%
  10. Levaquin: 5 people, 38.46%

What are other side effects people have besides Multiple injuries? *

  1. Stress And Anxiety: 11 people, 84.62%
  2. Pain: 10 people, 76.92%
  3. Headache (pain in head): 5 people, 38.46%
  4. Supraventricular Extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle): 5 people, 38.46%
  5. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 38.46%
  6. Acute Pulmonary Oedema (sudden deposit of fluid in the lung)): 5 people, 38.46%
  7. Weakness: 5 people, 38.46%
  8. Oedema Peripheral (superficial swelling): 4 people, 30.77%
  9. Acute Kidney Failure: 4 people, 30.77%
  10. Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 4 people, 30.77%

What are the existing conditions these people have? *

  1. Heart Rate Irregular: 4 people, 30.77%
  2. Osteoporosis (bones weak and more likely to break): 2 people, 15.38%
  3. Cardiac Failure Congestive: 2 people, 15.38%
  4. Upper Respiratory Tract Infection: 1 person, 7.69%
  5. Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 1 person, 7.69%
  6. Synovitis (inflammation of the synovial membrane): 1 person, 7.69%
  7. Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 7.69%
  8. Hypersensitivity: 1 person, 7.69%
  9. High Blood Cholesterol: 1 person, 7.69%
  10. Cardiac Disorder: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Arava and have Multiple injuries?

- Check whether Multiple injuries is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Arava:

Multiple injuries treatments and more:

How severe was Multiple injuries and when was it recovered:

Expand to all the drugs that have ingredients of leflunomide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Arava:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple injuries:

Browse all the conditions that are associated with Multiple injuries:


How the study uses the data?

The study uses data from the FDA. It is based on leflunomide (the active ingredients of Arava) and Arava (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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