Arava and Panic attacks - a phase IV clinical study of FDA data

Summary:

Panic attacks is reported as a side effect among people who take Arava (leflunomide), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Actemra, and have High blood pressure.

The phase IV clinical study analyzes which people have Panic attacks when taking Arava. It is created by eHealthMe based on reports of 75,674 people who have side effects when taking Arava from the FDA, and is updated regularly.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 76,040 Arava users. Check the latest studies of Arava.

What is Panic attacks?

Panic attacks is found to be associated with 2,284 drugs and 2,076 conditions by eHealthMe. Check the latest studies of Panic attacks.

On Apr, 21, 2026

75,674 people reported to have side effects when taking Arava.
Among them, 90 people (0.12%) have Panic attacks.

Among these 90 people:

How long have people been on Arava when they have Panic attacks? *

What is the gender of people who have Panic attacks when taking Arava? *

female: 74.68 %
male: 25.32 %

What is the age of people who have Panic attacks when taking Arava? *

What are other drugs people take besides Arava? *

What are other side effects people have besides Panic attacks? *

Stress And Anxiety: 65 people, 72.22%
Diarrhea: 54 people, 60.00%
Fatigue (feeling of tiredness): 52 people, 57.78%
Joint Pain: 51 people, 56.67%
Weakness: 51 people, 56.67%
Nausea (feeling of having an urge to vomit): 51 people, 56.67%
Abdominal Pain Upper: 48 people, 53.33%
Malaise (a feeling of general discomfort or uneasiness): 48 people, 53.33%
Thrombosis (formation of a blood clot inside a blood vessel): 47 people, 52.22%
Tremor (trembling or shaking movements in one or more parts of your body): 45 people, 50.00%

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 11.11%
Pain: 4 people, 4.44%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 4.44%
High Blood Cholesterol: 3 people, 3.33%
Allergic Rhinitis: 2 people, 2.22%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 2.22%
Muscle Aches (muscle pain): 2 people, 2.22%
Joint Pain: 2 people, 2.22%
Drowsiness: 1 person, 1.11%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 1.11%

* Approximation only. Some reports may have incomplete information.

Do you take Arava and have Panic attacks?

- Check whether Panic attacks is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Arava:

Arava (76,040 reports)

Panic attacks treatments and more:

Panic attacks (65,704 reports)

Browse all side effects of Arava:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Panic attacks:

Panic attacks (2,284 drugs)

Browse all the conditions that are associated with Panic attacks:

Panic attacks (2,076 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on leflunomide (the active ingredients of Arava) and Arava (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.