Arava and Renal function test abnormal - a phase IV clinical study of FDA data

Summary:

Renal function test abnormal is reported as a side effect among people who take Arava (leflunomide), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Xeljanz, and have Pain.

The phase IV clinical study analyzes which people have Renal function test abnormal when taking Arava. It is created by eHealthMe based on reports of 75,674 people who have side effects when taking Arava from the FDA, and is updated regularly.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 76,039 Arava users. Check the latest studies of Arava.

What is Renal function test abnormal?

Renal function test abnormal is found to be associated with 531 drugs and 556 conditions by eHealthMe. Check the latest studies of Renal function test abnormal.

On Nov, 20, 2025

75,674 people reported to have side effects when taking Arava.
Among them, 15 people (0.02%) have Renal function test abnormal.

Could Arava cause Renal function test abnormal?

Among these 15 people:

How long have people been on Arava when they have Renal function test abnormal? *

What is the gender of people who have Renal function test abnormal when taking Arava? *

female: 46.67 %
male: 53.33 %

What is the age of people who have Renal function test abnormal when taking Arava? *

What are other drugs people take besides Arava? *

What are other side effects people have besides Renal function test abnormal? *

Drug Ineffective: 12 people, 80.00%
Nausea (feeling of having an urge to vomit): 9 people, 60.00%
Fatigue (feeling of tiredness): 9 people, 60.00%
Night Sweats (sweating in night): 7 people, 46.67%
Cartilage Injury: 7 people, 46.67%
Grip Strength Decreased: 7 people, 46.67%
Tremor (trembling or shaking movements in one or more parts of your body): 7 people, 46.67%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 46.67%
Depression: 7 people, 46.67%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 5 people, 33.33%

What are the existing conditions these people have? *

Pain: 6 people, 40.00%
Pneumonia: 2 people, 13.33%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 13.33%
Back Pain: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Arava and have Renal function test abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Arava:

Arava (76,039 reports)

Browse all side effects of Arava:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Renal function test abnormal:

Renal function test abnormal (531 drugs)

Browse all the conditions that are associated with Renal function test abnormal:

Renal function test abnormal (556 conditions)

Drugs similar to Arava and Renal function test abnormal :

How the study uses the data?

The study uses data from the FDA. It is based on leflunomide (the active ingredients of Arava) and Arava (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.