Aredia and Aseptic necrosis - a phase IV clinical study of FDA data
Summary:
Aseptic necrosis is found among people who take Aredia, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years.
The phase IV clinical study analyzes which people take Aredia and have Aseptic necrosis. It is created by eHealthMe based on reports of 15,205 people who have side effects when taking Aredia from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
15,205 people reported to have side effects when taking Aredia.
Among them, 5,034 people (33.11%) have Aseptic necrosis.
What is Aredia?
Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,279 Aredia users for its effectiveness, alternative drugs and more.
What is Aseptic necrosis?
Aseptic necrosis (the death of bone tissue due to a lack of blood supply) is found to be associated with 2,253 drugs and 1,554 conditions by eHealthMe.
Number of Aredia and Aseptic necrosis reports submitted per year:

Time on Aredia when people have Aseptic necrosis *:
Gender of people who have Aseptic necrosis when taking Aredia*:
Age of people who have Aseptic necrosis when taking Aredia *:
Common drugs people take besides Aredia *:
Common side effects people have besides Aseptic necrosis *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Aredia and have Aseptic necrosis?
Check whether Aseptic necrosis is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Aseptic necrosis and when was it recovered:
Expand to all the drugs that have ingredients of pamidronate disodium:
Alternative drugs to, pros and cons of Aredia:
- Aredia (15,279 reports)
Common Aredia side effects:
- Pain: 5,860 reports
- Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 5,034 reports
- Stress and anxiety: 4,837 reports
- Osteomyelitis (infection of bone): 3,477 reports
Browse all side effects of Aredia:
a b c d e f g h i j k l m n o p q r s t u v w x y zAseptic necrosis treatments and more:
- Aseptic necrosis (55,247 reports)
COVID vaccines that are related to Aseptic necrosis:
- Aseptic necrosis in Moderna COVID Vaccine
- Aseptic necrosis in Pfizer BioNTech Covid Vaccine
- Aseptic necrosis in Johnson and Johnson Covid Vaccine
Common drugs associated with Aseptic necrosis:
- Truvada: 13,957 reports
- Zometa: 12,597 reports
- Viread: 12,106 reports
- Fosamax: 9,374 reports
- Atripla: 6,548 reports
- Aredia: 5,034 reports
- Descovy: 3,108 reports
- Genvoya: 3,077 reports
- Stribild: 3,004 reports
- Prednisone: 2,986 reports
All the drugs that are associated with Aseptic necrosis:
- Aseptic necrosis (2,253 drugs)
Common conditions associated with Aseptic necrosis:
- Hiv infection: 16,687 reports
- Osteoporosis: 6,757 reports
- Multiple myeloma: 3,445 reports
- Breast cancer: 1,907 reports
- High blood pressure: 1,391 reports
All the conditions that are associated with Aseptic necrosis:
- Aseptic necrosis (1,554 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on pamidronate disodium (the active ingredients of Aredia) and Aredia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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