Aredia and Fever - a phase IV clinical study of FDA data
Summary:
Fever is reported as a side effect among people who take Aredia (pamidronate disodium), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Zometa, and have Metastases to bone.
The phase IV clinical study analyzes which people have Fever when taking Aredia. It is created by eHealthMe based on reports of 15,280 people who have side effects when taking Aredia from the FDA, and is updated regularly.
What is Aredia?
Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,364 Aredia users. Check the latest studies of Aredia.
What is Fever?
Fever is found to be associated with 3,489 drugs and 6,141 conditions by eHealthMe. Check the latest studies of Fever.
15,280 people reported to have side effects when taking Aredia.
Among them, 1,967 people (12.87%) have Fever.

Among these 1,967 people:
How long have people been on Aredia when they have Fever? *
- < 1 month: 14.85 %
- 1 - 6 months: 10.74 %
- 6 - 12 months: 6.64 %
- 1 - 2 years: 19.43 %
- 2 - 5 years: 26.86 %
- 5 - 10 years: 19.59 %
- 10+ years: 1.9 %
What is the gender of people who have Fever when taking Aredia? *
- female: 62.73 %
- male: 37.27 %
What is the age of people who have Fever when taking Aredia? *
- 0-1: 0.78 %
- 2-9: 0.72 %
- 10-19: 1.08 %
- 20-29: 0.84 %
- 30-39: 2.93 %
- 40-49: 19.98 %
- 50-59: 34.57 %
- 60+: 39.06 %
What are other drugs people take besides Aredia? *
- Zometa: 1,367 people, 69.50%
- Protonix: 466 people, 23.69%
- Decadron: 446 people, 22.67%
- Coumadin: 444 people, 22.57%
- Thalidomide: 417 people, 21.20%
- Zofran: 413 people, 21.00%
- Prednisone: 411 people, 20.89%
- Neurontin: 399 people, 20.28%
- Ativan: 394 people, 20.03%
- Ambien: 384 people, 19.52%
What are other side effects people have besides Fever? *
- Pain: 1,229 people, 62.48%
- Stress And Anxiety: 1,136 people, 57.75%
- Osteonecrosis Of Jaw (death of bone of jaw): 1,109 people, 56.38%
- Bone Disorder: 925 people, 47.03%
- Anaemia (lack of blood): 830 people, 42.20%
- Back Pain: 829 people, 42.15%
- Weakness: 828 people, 42.09%
- Osteomyelitis (infection of bone): 808 people, 41.08%
- Fatigue (feeling of tiredness): 776 people, 39.45%
- Dyspnea (difficult or laboured breathing): 772 people, 39.25%
What are the existing conditions these people have? *
- Metastases To Bone (cancer spreads to bone): 343 people, 17.44%
- Pain: 134 people, 6.81%
- Osteoporosis (bones weak and more likely to break): 132 people, 6.71%
- Stress And Anxiety: 120 people, 6.10%
- High Blood Pressure: 110 people, 5.59%
- Anaemia (lack of blood): 69 people, 3.51%
- Depression: 62 people, 3.15%
- Breast Cancer Metastatic: 57 people, 2.90%
- Nausea (feeling of having an urge to vomit): 49 people, 2.49%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 39 people, 1.98%
* Approximation only. Some reports may have incomplete information.
Do you take Aredia and have Fever?
- Check whether Fever is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Aredia:
- Aredia (15,364 reports)
Fever treatments and more:
- Fever (498,662 reports)
How severe was Fever and when was it recovered:
Expand to all the drugs that have ingredients of pamidronate disodium:
- Fever and drugs with ingredients of pamidronate disodium (2,258 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Aredia side effects:
- Aredia side effect: Aseptic necrosis (the death of bone tissue due to a lack of blood supply) (5,034 reports)
- Aredia side effect: Osteonecrosis of jaw (death of bone of jaw) (4,469 reports)
- Aredia side effect: Bone disorder (4,314 reports)
- Aredia side effect: Osteomyelitis (infection of bone) (3,477 reports)
- Aredia side effect: Tooth extraction (3,435 reports)
Browse all side effects of Aredia:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Fever:
- Prednisone side effect: Fever (33,067 reports)
- Methotrexate side effect: Fever (25,283 reports)
- Humira side effect: Fever (21,395 reports)
- Aspirin side effect: Fever (15,311 reports)
- Enbrel side effect: Fever (15,185 reports)
- Pantoprazole side effect: Fever (14,394 reports)
- Omeprazole side effect: Fever (13,646 reports)
- Acetaminophen side effect: Fever (13,542 reports)
- Prednisolone side effect: Fever (12,573 reports)
- Tylenol side effect: Fever (12,465 reports)
Browse all the drugs that are associated with Fever:
- Fever (3,489 drugs)
Common conditions associated with Fever:
- Arthritis - rheumatoid: 27,612 reports
- Multiple sclerosis aggravated: 20,065 reports
- Hypertension aggravated: 16,478 reports
- Blood pressure - high: 16,380 reports
- Crohns disease: 14,102 reports
- Myeloma - multiple: 12,143 reports
- Pain exacerbated: 12,055 reports
- Pain relief: 11,762 reports
- Asthma: 9,798 reports
- Exercise-induced asthma: 9,742 reports
Browse all the conditions that are associated with Fever:
- Fever (6,141 conditions)
Drugs similar to Aredia and Fever :
Related publications that referenced our studies
- Schiller D, Maieron A, Sch?fl R, Donnerer J, "Drug fever due to a single dose of pantoprazole", Pharmacology, 2015 Jan .
- Schiller D, Maieron A, Sch?fl R, Donnerer J, "Drug fever due to a single dose of pantoprazole", Pharmacology, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on pamidronate disodium (the active ingredients of Aredia) and Aredia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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