Aredia and Macular fibrosis - a phase IV clinical study of FDA data

Summary:

Macular fibrosis is reported as a side effect among people who take Aredia (pamidronate disodium), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Zometa, and have Prostate cancer.

The phase IV clinical study analyzes which people have Macular fibrosis when taking Aredia. It is created by eHealthMe based on reports of 15,280 people who have side effects when taking Aredia from the FDA, and is updated regularly.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,365 Aredia users. Check the latest studies of Aredia.

What is Macular fibrosis?

Macular fibrosis (a thin sheet of scar tissue forms on top of the macula, in response to damage or injury) is found to be associated with 100 drugs and 436 conditions by eHealthMe. Check the latest studies of Macular fibrosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

15,280 people reported to have side effects when taking Aredia.
Among them, 12 people (0.08%) have Macular fibrosis.

Among these 12 people:

How long have people been on Aredia when they have Macular fibrosis? *

What is the gender of people who have Macular fibrosis when taking Aredia? *

female: 50 %
male: 50 %

What is the age of people who have Macular fibrosis when taking Aredia? *

What are other drugs people take besides Aredia? *

What are other side effects people have besides Macular fibrosis? *

Osteonecrosis Of Jaw (death of bone of jaw): 11 people, 91.67%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 11 people, 91.67%
Infection: 9 people, 75.00%
Pneumonia: 9 people, 75.00%
Pain: 9 people, 75.00%
Basal Cell Carcinoma (a skin cancer, it rarely metastasizes or kills): 9 people, 75.00%
Atelectasis (partial or complete collapse of the lung): 9 people, 75.00%
Osteitis (a general term for inflammation of bone): 9 people, 75.00%
Stress And Anxiety: 9 people, 75.00%
Fall: 9 people, 75.00%

What are the existing conditions these people have? *

Prostate Cancer: 4 people, 33.33%
Spinal Fracture (fracture in one of vertebrae): 2 people, 16.67%
Osteoporosis (bones weak and more likely to break): 2 people, 16.67%
Neuropathy Peripheral (surface nerve damage): 2 people, 16.67%
Multiple Fractures: 2 people, 16.67%
Lipids Increased (excess lipid in body): 2 people, 16.67%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 2 people, 16.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 16.67%
Pyoderma Gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance): 1 person, 8.33%
Metastases To Bone (cancer spreads to bone): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Aredia and have Macular fibrosis?

- Check whether Macular fibrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aredia:

Aredia (15,365 reports)

Browse all side effects of Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Macular fibrosis:

Macular fibrosis (100 drugs)

Browse all the conditions that are associated with Macular fibrosis:

Macular fibrosis (436 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pamidronate disodium (the active ingredients of Aredia) and Aredia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.