Aredia and Multiple sclerosis - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis is reported as a side effect among people who take Aredia (pamidronate disodium), especially for people who are female, 40-49 old, also take Clonidine, and have High blood pressure.

The phase IV clinical study analyzes which people have Multiple sclerosis when taking Aredia. It is created by eHealthMe based on reports of 15,280 people who have side effects when taking Aredia from the FDA, and is updated regularly.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,364 Aredia users. Check the latest studies of Aredia.

What is Multiple sclerosis?

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,087 drugs and 1,361 conditions by eHealthMe. Check the latest studies of Multiple sclerosis.

On Jul, 25, 2026

15,280 people reported to have side effects when taking Aredia.
Among them, 48 people (0.31%) have Multiple sclerosis.

Among these 48 people:

What is the gender of people who have Multiple sclerosis when taking Aredia? *

female: 93.75 %
male: 6.25 %

What is the age of people who have Multiple sclerosis when taking Aredia? *

What are other drugs people take besides Aredia? *

What are other side effects people have besides Multiple sclerosis? *

Osteonecrosis Of Jaw (death of bone of jaw): 41 people, 85.42%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 38 people, 79.17%
Osteomyelitis (infection of bone): 35 people, 72.92%
Swelling: 34 people, 70.83%
Stress And Anxiety: 32 people, 66.67%
Muscle Spasms (muscle contraction): 31 people, 64.58%
Joint Pain: 31 people, 64.58%
Pain: 31 people, 64.58%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 30 people, 62.50%
Pain In Extremity: 29 people, 60.42%

What are the existing conditions these people have? *

High Blood Pressure: 18 people, 37.50%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 35.42%
Pain: 11 people, 22.92%
Hypomania (a mild form of mania, marked by elation and hyperactivity): 11 people, 22.92%
Oedema (fluid collection in tissue): 11 people, 22.92%
Anaemia (lack of blood): 7 people, 14.58%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 7 people, 14.58%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 12.50%
Protein S Deficiency: 4 people, 8.33%
Diabetes: 2 people, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Aredia and have Multiple sclerosis?

- Check whether Multiple sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aredia:

Aredia (15,364 reports)

Browse all side effects of Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis:

Multiple sclerosis (1,087 drugs)

Browse all the conditions that are associated with Multiple sclerosis:

Multiple sclerosis (1,361 conditions)

Related publications that referenced our studies

Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .
Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on pamidronate disodium (the active ingredients of Aredia) and Aredia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.