Aredia and Muscle atrophy - a phase IV clinical study of FDA data
Summary:
Muscle atrophy is reported as a side effect among people who take Aredia (pamidronate disodium), especially for people who are female, 40-49 old, have been taking the drug for 5 - 10 years also take Zometa, and have Metastases to bone.
The phase IV clinical study analyzes which people have Muscle atrophy when taking Aredia. It is created by eHealthMe based on reports of 15,280 people who have side effects when taking Aredia from the FDA, and is updated regularly.
What is Aredia?
Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,365 Aredia users. Check the latest studies of Aredia.
What is Muscle atrophy?
Muscle atrophy (a decrease in the mass of the muscle) is found to be associated with 1,046 drugs and 1,963 conditions by eHealthMe. Check the latest studies of Muscle atrophy.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
15,280 people reported to have side effects when taking Aredia.
Among them, 81 people (0.53%) have Muscle atrophy.

Among these 81 people:
How long have people been on Aredia when they have Muscle atrophy? *
- < 1 month: 9.09 %
- 1 - 6 months: 4.55 %
- 6 - 12 months: 9.09 %
- 1 - 2 years: 4.55 %
- 2 - 5 years: 22.73 %
- 5 - 10 years: 50.0 %
- 10+ years: 0.0 %
What is the gender of people who have Muscle atrophy when taking Aredia? *
- female: 51.25 %
- male: 48.75 %
What is the age of people who have Muscle atrophy when taking Aredia? *
- 0-1: 0.0 %
- 2-9: 1.61 %
- 10-19: 3.23 %
- 20-29: 1.61 %
- 30-39: 1.61 %
- 40-49: 40.32 %
- 50-59: 29.03 %
- 60+: 22.58 %
What are other drugs people take besides Aredia? *
- Zometa: 63 people, 77.78%
- Dexamethasone: 30 people, 37.04%
- Prednisone: 29 people, 35.80%
- Ativan: 27 people, 33.33%
- Oxycontin: 27 people, 33.33%
- Celebrex: 26 people, 32.10%
- Thalidomide: 25 people, 30.86%
- Levaquin: 24 people, 29.63%
- Vicodin: 24 people, 29.63%
- Aspirin: 23 people, 28.40%
What are other side effects people have besides Muscle atrophy? *
- Pain: 72 people, 88.89%
- Osteonecrosis Of Jaw (death of bone of jaw): 65 people, 80.25%
- Stress And Anxiety: 57 people, 70.37%
- Pain In Jaw: 53 people, 65.43%
- Joint Pain: 52 people, 64.20%
- Osteomyelitis (infection of bone): 51 people, 62.96%
- Fatigue (feeling of tiredness): 51 people, 62.96%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 51 people, 62.96%
- Spinal Osteoarthritis (joint cartilage loss in spine): 48 people, 59.26%
- Atelectasis (partial or complete collapse of the lung): 47 people, 58.02%
What are the existing conditions these people have? *
- Metastases To Bone (cancer spreads to bone): 29 people, 35.80%
- Osteoporosis (bones weak and more likely to break): 15 people, 18.52%
- Behcet's Syndrome (involves inflammation of the blood vessels): 9 people, 11.11%
- Breast Cancer Metastatic: 9 people, 11.11%
- High Blood Pressure: 6 people, 7.41%
- Anaemia (lack of blood): 3 people, 3.70%
- Diabetes: 3 people, 3.70%
- High Blood Cholesterol: 3 people, 3.70%
- Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 3 people, 3.70%
- Seasonal Allergy (allergic condition due to certain season): 3 people, 3.70%
* Approximation only. Some reports may have incomplete information.
Do you take Aredia and have Muscle atrophy?
- Check whether Muscle atrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Aredia:
- Aredia (15,365 reports)
Muscle atrophy treatments and more:
- Muscle atrophy (15,319 reports)
How severe was Muscle atrophy and when was it recovered:
Expand to all the drugs that have ingredients of pamidronate disodium:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Aredia:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Muscle atrophy:
- Muscle atrophy (1,046 drugs)
Browse all the conditions that are associated with Muscle atrophy:
- Muscle atrophy (1,963 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on pamidronate disodium (the active ingredients of Aredia) and Aredia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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