Aredia and Obstructive uropathy - a phase IV clinical study of FDA data

Summary:

Obstructive uropathy is reported as a side effect among people who take Aredia (pamidronate disodium), especially for people who are male, 50-59 old, have been taking the drug for 5 - 10 years also take Zometa, and have Osteoporosis.

The phase IV clinical study analyzes which people have Obstructive uropathy when taking Aredia. It is created by eHealthMe based on reports of 15,280 people who have side effects when taking Aredia from the FDA, and is updated regularly.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,364 Aredia users. Check the latest studies of Aredia.

What is Obstructive uropathy?

Obstructive uropathy (a blockage that prevents urine from leaving your kidneys) is found to be associated with 180 drugs and 464 conditions by eHealthMe. Check the latest studies of Obstructive uropathy.

On Oct, 23, 2025

15,280 people reported to have side effects when taking Aredia.
Among them, 51 people (0.33%) have Obstructive uropathy.

Could Aredia cause Obstructive uropathy?

Among these 51 people:

How long have people been on Aredia when they have Obstructive uropathy? *

What is the gender of people who have Obstructive uropathy when taking Aredia? *

female: 32 %
male: 68 %

What is the age of people who have Obstructive uropathy when taking Aredia? *

What are other drugs people take besides Aredia? *

What are other side effects people have besides Obstructive uropathy? *

Osteonecrosis Of Jaw (death of bone of jaw): 49 people, 96.08%
Pain: 48 people, 94.12%
Spinal Osteoarthritis (joint cartilage loss in spine): 41 people, 80.39%
Fall: 39 people, 76.47%
Infection: 38 people, 74.51%
Bone Disorder: 37 people, 72.55%
Osteomyelitis (infection of bone): 35 people, 68.63%
Kidney Stones: 34 people, 66.67%
Nausea (feeling of having an urge to vomit): 33 people, 64.71%
Bone Pain: 33 people, 64.71%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 22 people, 43.14%
Metastases To Bone (cancer spreads to bone): 12 people, 23.53%
Prostate Cancer: 11 people, 21.57%
High Blood Cholesterol: 11 people, 21.57%
Muscle Spasms (muscle contraction): 3 people, 5.88%
Depression: 3 people, 5.88%
Breast Cancer Metastatic: 3 people, 5.88%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 2 people, 3.92%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 3.92%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 1 person, 1.96%

* Approximation only. Some reports may have incomplete information.

Do you take Aredia and have Obstructive uropathy?

- Check whether Obstructive uropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aredia:

Aredia (15,364 reports)

Browse all side effects of Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Obstructive uropathy:

Obstructive uropathy (180 drugs)

Browse all the conditions that are associated with Obstructive uropathy:

Obstructive uropathy (464 conditions)

Drugs similar to Aredia and Obstructive uropathy :

How the study uses the data?

The study uses data from the FDA. It is based on pamidronate disodium (the active ingredients of Aredia) and Aredia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.