Aredia and Periorbital oedema - a phase IV clinical study of FDA data

Summary:

Periorbital oedema is reported as a side effect among people who take Aredia (pamidronate disodium), especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years also take Zometa, and have Depression.

The phase IV clinical study analyzes which people have Periorbital oedema when taking Aredia. It is created by eHealthMe based on reports of 15,280 people who have side effects when taking Aredia from the FDA, and is updated regularly.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,365 Aredia users. Check the latest studies of Aredia.

What is Periorbital oedema?

Periorbital oedema (swelling around the eyes) is found to be associated with 547 drugs and 655 conditions by eHealthMe. Check the latest studies of Periorbital oedema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

15,280 people reported to have side effects when taking Aredia.
Among them, 17 people (0.11%) have Periorbital oedema.

Among these 17 people:

How long have people been on Aredia when they have Periorbital oedema? *

What is the gender of people who have Periorbital oedema when taking Aredia? *

female: 58.82 %
male: 41.18 %

What is the age of people who have Periorbital oedema when taking Aredia? *

What are other drugs people take besides Aredia? *

What are other side effects people have besides Periorbital oedema? *

Osteonecrosis Of Jaw (death of bone of jaw): 16 people, 94.12%
Stress And Anxiety: 16 people, 94.12%
Bone Disorder: 14 people, 82.35%
Pain: 13 people, 76.47%
Infection: 13 people, 76.47%
Injury: 13 people, 76.47%
Depression: 13 people, 76.47%
Anaemia (lack of blood): 12 people, 70.59%
Back Pain: 11 people, 64.71%
Pain In Extremity: 11 people, 64.71%

What are the existing conditions these people have? *

Depression: 3 people, 17.65%
Acute Kidney Failure: 2 people, 11.76%
High Blood Pressure: 1 person, 5.88%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 1 person, 5.88%
Blood Iron Increased: 1 person, 5.88%
Breast Cancer Metastatic: 1 person, 5.88%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 5.88%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 5.88%
Traumatic Injury Of The Bladder And Urethra: 1 person, 5.88%
Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Aredia and have Periorbital oedema?

- Check whether Periorbital oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aredia:

Aredia (15,365 reports)

Browse all side effects of Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Periorbital oedema:

Periorbital oedema (547 drugs)

Browse all the conditions that are associated with Periorbital oedema:

Periorbital oedema (655 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pamidronate disodium (the active ingredients of Aredia) and Aredia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.