Aricept and Diastolic dysfunction - a phase IV clinical study of FDA data

Summary:

Diastolic dysfunction is reported as a side effect among people who take Aricept (donepezil hydrochloride), especially for people who are male, 60+ old, also take Coreg, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Diastolic dysfunction when taking Aricept. It is created by eHealthMe based on reports of 23,732 people who have side effects when taking Aricept from the FDA, and is updated regularly.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

What is Diastolic dysfunction?

Diastolic dysfunction is found to be associated with 682 drugs and 630 conditions by eHealthMe. Check the latest studies of Diastolic dysfunction.

On Jul, 12, 2026

23,732 people reported to have side effects when taking Aricept.
Among them, 22 people (0.09%) have Diastolic dysfunction.

Could Aricept cause Diastolic dysfunction?

Among these 22 people:

What is the gender of people who have Diastolic dysfunction when taking Aricept? *

female: 22.73 %
male: 77.27 %

What is the age of people who have Diastolic dysfunction when taking Aricept? *

What are other drugs people take besides Aricept? *

What are other side effects people have besides Diastolic dysfunction? *

Weakness: 13 people, 59.09%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 13 people, 59.09%
Left Ventricular Hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 12 people, 54.55%
Cardiac Failure Congestive: 11 people, 50.00%
Oedema Peripheral (superficial swelling): 11 people, 50.00%
Weight Increased: 9 people, 40.91%
Stress And Anxiety: 9 people, 40.91%
Dizziness: 9 people, 40.91%
Bradycardia (abnormally slow heart action): 9 people, 40.91%
Fatigue (feeling of tiredness): 9 people, 40.91%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 31.82%
Depression: 5 people, 22.73%
Pain: 2 people, 9.09%
Type 2 Diabetes: 2 people, 9.09%
Wound: 1 person, 4.55%
Genital Herpes (herpes infection of genital): 1 person, 4.55%
Cardiac Failure: 1 person, 4.55%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 4.55%
Cervix Carcinoma (cancer of cervix): 1 person, 4.55%
Diabetes: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Aricept and have Diastolic dysfunction?

- Check whether Diastolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aricept:

Aricept (24,756 reports)

Browse all side effects of Aricept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diastolic dysfunction:

Diastolic dysfunction (682 drugs)

Browse all the conditions that are associated with Diastolic dysfunction:

Diastolic dysfunction (630 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on donepezil hydrochloride (the active ingredients of Aricept) and Aricept (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.