Aricept and Hypertensive crisis - a phase IV clinical study of FDA data

Summary:

Hypertensive crisis is reported as a side effect among people who take Aricept (donepezil hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Namenda, and have Dementia alzheimer's type.

The phase IV clinical study analyzes which people have Hypertensive crisis when taking Aricept. It is created by eHealthMe based on reports of 23,732 people who have side effects when taking Aricept from the FDA, and is updated regularly.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

What is Hypertensive crisis?

Hypertensive crisis is found to be associated with 783 drugs and 932 conditions by eHealthMe. Check the latest studies of Hypertensive crisis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

23,732 people reported to have side effects when taking Aricept.
Among them, 41 people (0.17%) have Hypertensive crisis.

Could Aricept cause Hypertensive crisis?

Among these 41 people:

How long have people been on Aricept when they have Hypertensive crisis? *

What is the gender of people who have Hypertensive crisis when taking Aricept? *

female: 75.61 %
male: 24.39 %

What is the age of people who have Hypertensive crisis when taking Aricept? *

What are other drugs people take besides Aricept? *

What are other side effects people have besides Hypertensive crisis? *

Confusional State: 10 people, 24.39%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 7 people, 17.07%
Confusion: 7 people, 17.07%
Bradycardia (abnormally slow heart action): 6 people, 14.63%
Hypotension (abnormally low blood pressure): 6 people, 14.63%
Nausea And Vomiting: 6 people, 14.63%
Infection: 5 people, 12.20%
Nausea (feeling of having an urge to vomit): 5 people, 12.20%
Catatonia (unresponsive to external stimuli): 5 people, 12.20%
Feeling Abnormal: 5 people, 12.20%

What are the existing conditions these people have? *

Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 8 people, 19.51%
Delusion (a false belief or opinion): 3 people, 7.32%
High Blood Pressure: 3 people, 7.32%
Nephrogenic Anaemia (anaemia due to kidney disease): 2 people, 4.88%
Vulvovaginal Dryness: 1 person, 2.44%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 2.44%
Atrophic Vulvovaginitis (inflammation of the vulva): 1 person, 2.44%
Confusional State: 1 person, 2.44%
Depression: 1 person, 2.44%
Diabetes: 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Aricept and have Hypertensive crisis?

- Check whether Hypertensive crisis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aricept:

Aricept (24,756 reports)

Browse all side effects of Aricept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertensive crisis:

Hypertensive crisis (783 drugs)

Browse all the conditions that are associated with Hypertensive crisis:

Hypertensive crisis (932 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on donepezil hydrochloride (the active ingredients of Aricept) and Aricept (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.