Aricept and Hypertonic bladder - a phase IV clinical study of FDA data

Summary:

Hypertonic bladder is reported as a side effect among people who take Aricept (donepezil hydrochloride), especially for people who are female, 60+ old, also take Restoril, and have Depression.

The phase IV clinical study analyzes which people have Hypertonic bladder when taking Aricept. It is created by eHealthMe based on reports of 23,732 people who have side effects when taking Aricept from the FDA, and is updated regularly.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

What is Hypertonic bladder?

Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate) is found to be associated with 593 drugs and 520 conditions by eHealthMe. Check the latest studies of Hypertonic bladder.

On Jul, 02, 2026

23,732 people reported to have side effects when taking Aricept.
Among them, 17 people (0.07%) have Hypertonic bladder.

Among these 17 people:

What is the gender of people who have Hypertonic bladder when taking Aricept? *

female: 64.71 %
male: 35.29 %

What is the age of people who have Hypertonic bladder when taking Aricept? *

What are other drugs people take besides Aricept? *

What are other side effects people have besides Hypertonic bladder? *

Weakness: 12 people, 70.59%
Pain: 10 people, 58.82%
Fall: 9 people, 52.94%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 52.94%
Stress And Anxiety: 8 people, 47.06%
Oedema Peripheral (superficial swelling): 7 people, 41.18%
Fatigue (feeling of tiredness): 7 people, 41.18%
High Blood Pressure: 6 people, 35.29%
Fever: 6 people, 35.29%
Enlarged Heart: 6 people, 35.29%

What are the existing conditions these people have? *

Depression: 4 people, 23.53%
Pain: 3 people, 17.65%
High Blood Cholesterol: 2 people, 11.76%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 11.76%
Breast Cancer: 2 people, 11.76%
Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 11.76%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 11.76%
Multiple Myeloma (cancer of the plasma cells): 2 people, 11.76%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 11.76%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Aricept and have Hypertonic bladder?

- Check whether Hypertonic bladder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aricept:

Aricept (24,756 reports)

Browse all side effects of Aricept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertonic bladder:

Hypertonic bladder (593 drugs)

Browse all the conditions that are associated with Hypertonic bladder:

Hypertonic bladder (520 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on donepezil hydrochloride (the active ingredients of Aricept) and Aricept (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.