Aricept and Neuroleptic malignant syndrome - a phase IV clinical study of FDA data
Summary:
Neuroleptic malignant syndrome is reported as a side effect among people who take Aricept (donepezil hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Seroquel, and have Dementia alzheimer's type.
The phase IV clinical study analyzes which people have Neuroleptic malignant syndrome when taking Aricept. It is created by eHealthMe based on reports of 23,732 people who have side effects when taking Aricept from the FDA, and is updated regularly.
What is Aricept?
Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.
What is Neuroleptic malignant syndrome?
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents) is found to be associated with 551 drugs and 771 conditions by eHealthMe. Check the latest studies of Neuroleptic malignant syndrome.
23,732 people reported to have side effects when taking Aricept.
Among them, 145 people (0.61%) have Neuroleptic malignant syndrome.

Among these 145 people:
How long have people been on Aricept when they have Neuroleptic malignant syndrome? *
What is the gender of people who have Neuroleptic malignant syndrome when taking Aricept? *
What is the age of people who have Neuroleptic malignant syndrome when taking Aricept? *
What are other drugs people take besides Aricept? *
What are other side effects people have besides Neuroleptic malignant syndrome? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Aricept and have Neuroleptic malignant syndrome?
- Check whether Neuroleptic malignant syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Aricept:
- Aricept (24,756 reports)
Neuroleptic malignant syndrome treatments and more:
- Neuroleptic malignant syndrome (15,573 reports)
How severe was Neuroleptic malignant syndrome and when was it recovered:
Expand to all the drugs that have ingredients of donepezil hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Aricept:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Neuroleptic malignant syndrome:
- Neuroleptic malignant syndrome (551 drugs)
Browse all the conditions that are associated with Neuroleptic malignant syndrome:
- Neuroleptic malignant syndrome (771 conditions)
Related publications that referenced our studies
- Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
- Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on donepezil hydrochloride (the active ingredients of Aricept) and Aricept (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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